Current and future advances in surgical therapy for pituitary adenoma

DZ Khan, JG Hanrahan, SE Baldeweg… - Endocrine …, 2023 - academic.oup.com
The vital physiological role of the pituitary gland, alongside its proximity to critical
neurovascular structures, means that pituitary adenomas can cause significant morbidity or …

Predictors of response to treatment with first-generation somatostatin receptor ligands in patients with acromegaly

M Marques-Pamies, J Gil, M Jordà… - Archives of Medical …, 2023 - Elsevier
Background and Aims Predictors of first-generation somatostatin receptor ligands (fgSRLs)
response in acromegaly have been studied for over 30 years, but they are still not …

Prolactin and growth hormone signaling and interlink focused on the mammosomatotroph paradigm: a comprehensive review of the literature

M Araujo-Castro, M Marazuela… - International Journal of …, 2023 - mdpi.com
Prolactin (PRL) and growth hormone (GH) are peptide hormones that bind to the class 1
cytokine receptor superfamily, a highly conserved cell surface class of receptors. Both …

The Multibiomarker Acro-TIME Score Predicts fg-SRLs Response: Preliminary Results of a Retrospective Acromegaly Cohort

S Chiloiro, R Moroni, A Giampietro… - The Journal of …, 2024 - academic.oup.com
Context The prompt control of acromegaly is a primary treatment aim for reducing related
disease morbidity and mortality. First-generation somatostatin receptor ligands (fg-SRLs) are …

Dissecting the in vitro efficacy of octreotide and cabergoline in GH-and GH/PRL-secreting pituitary tumors

F Gatto, RA Feelders, PM van Koetsveld… - The Journal of …, 2023 - academic.oup.com
Context Cabergoline (CAB) is an off-label medical therapy for acromegaly, overshadowed
by first-generation somatostatin receptor ligands, eg, octreotide (OCT). Objective This was a …

Predictors of biochemical response to somatostatin receptor ligands in acromegaly

M Marazuela, R Martínez-Hernandez… - Best Practice & …, 2024 - Elsevier
Although predictors of response to first-generation somatostatin receptor ligands (fg-SRLs),
and to a lesser extent to pasireotide, have been studied in acromegaly for many years, their …

Leukocyte Telomere Length and Neuregulin-4 Levels in Female Patients with Acromegaly: The Relationship between Disease Activity and Body Fat Distribution

M Coskun, AE Altinova, A Babayeva, AT Sel… - Journal of clinical …, 2023 - mdpi.com
The study aimed to examine leukocyte telomere length (LTL) and serum neuregulin-4 levels
and their relationship with disease activity, co-morbidities and body fat distribution in female …

Unveiling Precision Medicine with Data Mining: Discovering Patient Subgroups and Patterns

NS Mosavi, MF Santos - 2023 IEEE Symposium Series on …, 2023 - ieeexplore.ieee.org
Data mining techniques, prominently clustering, assume a pivotal role in fortifying precision
medicine by facilitating the revelation of patient subgroups that share common attributes. By …

[HTML][HTML] Visualization and Analysis of the Data Mining Domain of Scientific Medical Publications in the Web of Science Database Using Co-word Analysis

F Osareh, N AtaeeNasab, AF Pahlo - Jundishapur Journal of Health …, 2023 - brieflands.com
Background: The present study aims at visualizing and analyzing the scientific productions
of data mining in medical sciences in the Web of Science (WoS) database to identify …

[HTML][HTML] Using a Precision Approach to Optimize the Drug Therapy of Patients With Acromegaly Syndrome

VS Pronin, MB Antsiferov, TM Alekseeva… - The Pituitary Gland-An …, 2023 - intechopen.com
Modern problems of acromegaly treatment are associated with the heterogeneous
composition of somatotrophic tumors, differing in clinical course and sensitivity to the …