Recent Insights into the Pathophysiology of Narcolepsy Type 1

M Vringer, J Zhou, JK Gool, D Bijlenga… - Sleep Medicine …, 2024 - Elsevier
Summary Narcolepsy type 1 (NT1) is a sleep-wake disorder in which people typically
experience excessive daytime sleepiness, cataplexy and other sleep-wake disturbances …

Data-driven phenotyping of central disorders of hypersomnolence with unsupervised clustering

JK Gool, Z Zhang, MSSL Oei, S Mathias, Y Dauvilliers… - Neurology, 2022 - AAN Enterprises
Background and Objectives Recent studies fueled doubts as to whether all currently defined
central disorders of hypersomnolence are stable entities, especially narcolepsy type 2 and …

Changed cerebral white matter structural network topological characters and its correlation with cognitive behavioral abnormalities in narcolepsy type 1

K Ni, Y Liu, X Zhu, H Tan, Y Zeng, Q Guo… - Nature and Science …, 2022 - Taylor & Francis
Objective In the current study we investigated topological abnormalities of the cerebral white
matter networks in narcolepsy type 1 (NT1) patients and its relationship with their cognitive …

White matter integrity in narcolepsy: the structural blueprint for functional complaints?

JK Gool, TT Dang-Vu, YD van der Werf - Sleep, 2024 - academic.oup.com
Narcolepsy is a chronic neurological sleep disorder characterized by excessive daytime
sleepiness and is generally divided into two subtypes: narcolepsy type 1 and type 2 …

How Sleep Affects Daytime Functioning: The Latest Insights from Different Patient and Age Groups

E Altena, JG Ellis - Brain Sciences, 2021 - mdpi.com
Sleep problems can have a major impact on daytime functioning across all domains (ie,
cognitive, affective and physical). It can affect attention, concentration and higher cognitive …

Abnormal Brain Network Topology During Non–rapid Eye Movement Sleep and Its Correlation With Cognitive Behavioral Abnormalities in Narcolepsy Type 1

X Zhu, K Ni, H Tan, Y Liu, Y Zeng, B Yu, Q Guo… - Frontiers in …, 2021 - frontiersin.org
Objective: Simultaneous electroencephalography (EEG) and functional magnetic resonance
imaging (fMRI) were applied to investigate the abnormalities in the topological …

[PDF][PDF] 1 型发作性睡病非快速眼动睡眠期脑网络拓扑特征及其与认知行为评价的相关性

朱晓宇, 倪坤林, 谭慧文, 刘奕姝, 曾尹, 郭启勇, 肖莉… - 磁共振成像, 2021 - med-sci.cn
目的应用同步脑电-功能磁共振成像技术(electroencephalography-functional magnetic
resonance imaging, EEG-fMRI), 探讨1 型发作性睡病(narcolepsy type 1, NT1) …

Enhanced Visual Cortex Activation in People With Narcolepsy Type 1 During Active Sleep Resistance: An fMRI-EEG Study

JK Gool, R Fronczek, P Bosma… - Frontiers in …, 2022 - frontiersin.org
The brain activation patterns related to sleep resistance remain to be discovered in health
and disease. The maintenance of wakefulness test (MWT) is an objective …

An Analysis of the Influence of Background Music on the Sustained Attention of College Students using the Sustained Attention to Response Task (SART)

R Browne - 2023 - norma.ncirl.ie
Aims: In order to better understand the way in which background music influences cognitive
states such as sustained attention, this study set out to examine attentional states during the …

[HTML][HTML] Exploring the Intersection of Narcolepsy and Attention Deficit Hyperactivity Disorder: Similarities, Differences, and Clinical Implications

SH Yoon, YC Kim, HJ Seo, TW Kim… - Sleep Medicine …, 2024 - sleepmedres.org
Narcolepsy and attention deficit hyperactivity disorder (ADHD) are distinct neurobiological
conditions characterized by overlapping symptoms, including excessive daytime sleepiness …