Metagenomics and future perspectives in virus discovery

JL Mokili, F Rohwer, BE Dutilh - Current opinion in virology, 2012 - Elsevier
Monitoring the emergence and re-emergence of viral diseases with the goal of containing
the spread of viral agents requires both adequate preparedness and quick response …

Worlds within worlds: evolution of the vertebrate gut microbiota

RE Ley, CA Lozupone, M Hamady, R Knight… - Nature Reviews …, 2008 - nature.com
In this Analysis we use published 16S ribosomal RNA gene sequences to compare the
bacterial assemblages that are associated with humans and other mammals, metazoa and …

Fast UniFrac: facilitating high-throughput phylogenetic analyses of microbial communities including analysis of pyrosequencing and PhyloChip data

M Hamady, C Lozupone, R Knight - The ISME journal, 2010 - academic.oup.com
Next-generation sequencing techniques, and PhyloChip, have made simultaneous
phylogenetic analyses of hundreds of microbial communities possible. Insight into …

Marine viruses: truth or dare

M Breitbart - Annual review of marine science, 2012 - annualreviews.org
Over the past two decades, marine virology has progressed from a curiosity to an intensely
studied topic of critical importance to oceanography. At concentrations of approximately 10 …

Laboratory procedures to generate viral metagenomes

RV Thurber, M Haynes, M Breitbart, L Wegley… - Nature protocols, 2009 - nature.com
This collection of laboratory protocols describes the steps to collect viruses from various
samples with the specific aim of generating viral metagenome sequence libraries (viromes) …

Viruses manipulate the marine environment

F Rohwer, RV Thurber - Nature, 2009 - nature.com
Abstract Marine viruses affect Bacteria, Archaea and eukaryotic organisms and are major
components of the marine food web. Most studies have focused on their role as predators …

Expanding the RNA virosphere by unbiased metagenomics

YZ Zhang, YM Chen, W Wang, XC Qin… - Annual Review of …, 2019 - annualreviews.org
Although viruses comprise the most abundant genetic material in the biosphere, to date only
several thousand virus species have been formally defined. Such a limited perspective on …

Predicting virus emergence amid evolutionary noise

JL Geoghegan, EC Holmes - Open biology, 2017 - royalsocietypublishing.org
The study of virus disease emergence, whether it can be predicted and how it might be
prevented, has become a major research topic in biomedicine. Here we show that efforts to …

Viral and microbial community dynamics in four aquatic environments

B Rodriguez-Brito, LL Li, L Wegley, M Furlan… - The ISME …, 2010 - academic.oup.com
The species composition and metabolic potential of microbial and viral communities are
predictable and stable for most ecosystems. This apparent stability contradicts theoretical …

High diversity of the viral community from an Antarctic lake

A López-Bueno, J Tamames, D Velázquez, A Moya… - Science, 2009 - science.org
Viruses are the most abundant biological entities and can control microbial communities, but
their identity in terrestrial and freshwater Antarctic ecosystems is unknown. The genetic …