Anticancer potential of the plant‐derived Saponin Gracillin: a comprehensive review of mechanistic approaches

MS Bhuia, R Chowdhury, FA Sonia… - Chemistry & …, 2023 - Wiley Online Library
With the increasing prevalence of cancer and the toxic side effects of synthetic drugs, natural
products are being developed as promising therapeutic approaches. Gracillin is a naturally …

The efficacy of natural bioactive compounds against prostate cancer: Molecular targets and synergistic activities

MAR Mia, D Dey, MR Sakib, MY Biswas… - Phytotherapy …, 2023 - Wiley Online Library
Globally, prostate cancer (PCa) is regarded as a challenging health issue, and the number
of PCa patients continues to rise despite the availability of effective treatments in recent …

Metabolomic profile, anti-trypanosomal potential and molecular docking studies of Thunbergia grandifolia

HAS El-Nashar, AM Sayed… - Journal of Enzyme …, 2023 - Taylor & Francis
Trypanosomiasis is a protozoan disease transmitted via Trypanosoma brucei. This study
aimed to examine the metabolic profile and anti-trypanosomal effect of methanol extract of …

[HTML][HTML] Phytochemical profiling and neuroprotective activity of Callistemon subulatus leaves against cyclophosphamide-induced chemobrain

O Rabie, HAS El-Nashar, MY George… - Biomedicine & …, 2023 - Elsevier
Cyclophosphamide (CPA) is a chemotherapeutic drug used for various types of cancers.
However, patients receiving CPA for long periods suffer cognitive impairment associated …

Chemical composition, seasonal variation and antiaging activities of essential oil from Callistemon subulatus leaves growing in Egypt

O Rabie, HAS El-Nashar, TA Majrashi… - Journal of enzyme …, 2023 - Taylor & Francis
Callistemon is an aromatic genus of flowering plants belonging to family Myrtaceae. The
essential oils of C. subulatus leaves were collected in four seasons and analyzed using …

Antioxidant and Pulmonary Protective Potential of Fraxinus xanthoxyloides Bark Extract against CCl4‐Induced Toxicity in Rats

T Younis, F Jabeen, A Hussain, B Rasool… - Chemistry & …, 2023 - Wiley Online Library
Fraxinus xanthoxyloides is a perennial shrub belonging to family Oleaceae, traditionally
used for malaria, jaundice, pneumonia, inflammation, and rheumatism. Our study is aimed to …

Quercetin increases the antidepressant‐like effects of sclareol and antagonizes diazepam in thiopental sodium‐induced sleeping mice: a possible GABAergic …

MH Bappi, MN Mia, SA Ansari, IA Ansari… - Phytotherapy …, 2024 - Wiley Online Library
Quercetin is the most common polyphenolic flavonoid present in fruits and vegetables
demonstrating versatile health‐promoting effects. This study aimed to examine the effects of …

Brazilin: An updated literature-based review on its promising therapeutic approaches and toxicological studies

S Jamaddar, C Sarkar, S Akter, MS Mubarak… - South African Journal of …, 2023 - Elsevier
Introduction Brazilin is a promising natural red dye, extracted from the wood of Caesalpinia
sappan L. It exhibits several pharmacological activities including anti-inflammatory …

Polysaccharides (pectin, mucilage, and fructan inulin) and their fermented products: a critical analysis of their biochemical, gut interactions, and biological functions as …

HAS El‐Nashar, M Taleb, M EL‐Shazly… - Phytotherapy …, 2024 - Wiley Online Library
Diabetes mellitus is a globally metabolic endocrine syndrome marked by a deficiency of
insulin secretion (type‐1 DM) or glucose intolerance arising from insulin response …

Anti-inflammatory effects of thymol: an emphasis on the molecular interactions through in vivo approach and molecular dynamic simulations

MT Islam, MH Bappi, MS Bhuia, SA Ansari… - Frontiers in …, 2024 - frontiersin.org
Thymol (THY), as the natural monoterpene phenol, acts against oxidative stress and
inflammatory processes. This study aimed to evaluate the anti-inflammatory effects and …