MicroRNAs and complex diseases: from experimental results to computational models
Plenty of microRNAs (miRNAs) were discovered at a rapid pace in plants, green algae,
viruses and animals. As one of the most important components in the cell, miRNAs play a …
viruses and animals. As one of the most important components in the cell, miRNAs play a …
Endocrine disruptors acting on estrogen and androgen pathways cause reproductive disorders through multiple mechanisms: a review
Increasing contamination of the environment by toxic compounds such as endocrine
disrupting chemicals (EDCs) is one of the major causes of reproductive defects in both …
disrupting chemicals (EDCs) is one of the major causes of reproductive defects in both …
Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases
Dysregulated expression of microRNAs (miRNAs) in various tissues has been associated
with a variety of diseases, including cancers. Here we demonstrate that miRNAs are present …
with a variety of diseases, including cancers. Here we demonstrate that miRNAs are present …
The role of microRNA-185 in the pathogenesis of human diseases: a focus on cancer
MicroRNAs (miRNAs) are a widely-studied class of non-coding RNAs characterized by their
short length (18-25 nucleotides). The precise functions of miRNAs are not well-elucidated; …
short length (18-25 nucleotides). The precise functions of miRNAs are not well-elucidated; …
Integrated profiling of microRNAs and mRNAs: microRNAs located on Xq27. 3 associate with clear cell renal cell carcinoma
Background With the advent of second-generation sequencing, the expression of gene
transcripts can be digitally measured with high accuracy. The purpose of this study was to …
transcripts can be digitally measured with high accuracy. The purpose of this study was to …
Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells
M Yang, J Chen, F Su, B Yu, F Su, L Lin, Y Liu… - Molecular cancer, 2011 - Springer
Abstract Background Tumor-associated macrophages (TAMs) are alternatively activated
cells induced by interleukin-4 (IL-4)-releasing CD4+ T cells. TAMs promote breast cancer …
cells induced by interleukin-4 (IL-4)-releasing CD4+ T cells. TAMs promote breast cancer …
A robust methodology to study urine microRNA as tumor marker: microRNA-126 and microRNA-182 are related to urinary bladder cancer
M Hanke, K Hoefig, H Merz, AC Feller, I Kausch… - … oncology: seminars and …, 2010 - Elsevier
OBJECTIVES: MicroRNAs have been shown to be related to specific types of malignant cell
growth. In case of urothelial bladder cancer (BCa), novel noninvasive diagnosis is …
growth. In case of urothelial bladder cancer (BCa), novel noninvasive diagnosis is …
MicroRNAs: key players in the immune system, differentiation, tumorigenesis and cell death
R Schickel, B Boyerinas, SM Park, ME Peter - Oncogene, 2008 - nature.com
Micro (mi) RNAs are small, highly conserved noncoding RNAs that control gene expression
post-transcriptionally either via the degradation of target mRNAs or the inhibition of protein …
post-transcriptionally either via the degradation of target mRNAs or the inhibition of protein …
MicroRNA in prostate, bladder, and kidney cancer: a systematic review
CONTEXT: MicroRNAs (miRNA) are noncoding RNAs that post-transcriptionally regulate
gene expression. Their altered expression and function have been observed in most …
gene expression. Their altered expression and function have been observed in most …
Coordinate regulation of FOXO1 by miR-27a, miR-96, and miR-182 in breast cancer cells
IK Guttilla, BA White - Journal of Biological Chemistry, 2009 - ASBMB
The FOXO1 transcription factor orchestrates the regulation of genes involved in the apoptotic
response, cell cycle checkpoints, and cellular metabolism. FOXO1 is a putative tumor …
response, cell cycle checkpoints, and cellular metabolism. FOXO1 is a putative tumor …