The development of new safe and effective contrast agents (CAs) is a crucial factor to
increase the effectiveness of computed tomography (CT). For now, tantalum oxide-based …

The benefit of small animal imaging is directly linked to the validity and reliability of the
collected data. If the data (regardless of the modality used) are not reproducible and/or …

Here, we describe the synthesis, characterization and in vitro and in vivo performance of a
series of tantalum oxide (TaOx) based nanoparticles (NPs) for computed tomography (CT) …

Medical imaging is widely used clinically and in research to understand disease progression
and monitor responses to therapies. Vascular imaging enables the study of vascular disease …

Wegener granulomatosis is a rare disease of unknown aetiology. In the majority of these
patients the kidney is involved in the disease process. We performed a case-control study to …

Vascular research is largely performed in rodents with the goal of developing treatments for
human disease. Micro-computed tomography (micro-CT) provides non-destructive three …

Rationale: In vivo molecular imaging in preclinical animal models is a tool of choice for
understanding the pathophysiological mechanisms involved in cancer development and for …

The gold-standard of preclinical micro-computed tomography (μCT) data processing is still
manual delineation of complete organs or regions by specialists. However, this method is …

Objectives Computed tomography (CT) imaging is considered relatively safe and is often
used in preclinical research to study physiological processes. However, the sum of low-dose …

Ultrasmall heavy metal oxide nanoparticles are potential candidate materials for X-ray
computed tomography (CT) contrast agents because they possess high X-ray attenuation …