Progress in the field of prosthetic cardiovascular devices has significantly contributed to the
rapid advancements in cardiac therapy during the last four decades. The concept of …

Ventricular assist devices (VADs) have already helped many patients with heart failure but
have the potential to assist more patients if current problems with blood damage (hemolysis …

Modeling of the cardiovascular system is challenging, but it has the potential to further
advance our understanding of normal and pathological conditions. Morphology and function …

This study is part of a FDA-sponsored project to evaluate the use and limitations of
computational fluid dynamics (CFD) in assessing blood flow parameters related to medical …

An extended pattern search approach is presented for the optimization of the placement of
wind turbines on a wind farm. Problem-specific extensions infuse stochastic characteristics …

Background Modelling and simulation may become clinically applicable tools for detailed
evaluation of the cardiovascular system and clinical decision-making to guide therapeutic …

Objective To investigate potentially prothrombotic flow patterns within an axial flow
ventricular assist device under clinically relevant pulsatile hemodynamic conditions …

A multiplicity of secondary flow morphologies is produced in the arterial network due to
complexities in geometry (such as curvature, branching, and tortuosity) and pulsatility in the …

Secondary flows within curved arteries with unsteady forcing result from amplified centrifugal
instabilities and are expected to be driven by the rapid accelerations and decelerations …

BACKGROUND: Continuous-flow (CF) ventricular assist devices (VAD) are an established
option for treatment of end-stage heart failure. However, the effect of long-term CF with lack …