Multicenter proteome-wide Mendelian randomization study identifies causal plasma proteins in melanoma and non-melanoma skin cancers

Y Li, Q Li, Z Cao, J Wu - Communications Biology, 2024 - nature.com
This study addresses the diagnostic and therapeutic challenges in malignant melanoma
(MM) and non-melanoma skin cancers (NMSC). We aim to identify circulating proteins …

Genomic and clinical characterization of pediatric lymphoepithelioma-like carcinoma

Y Que, X Lu, S Lu, F Sun, J Zhu, Y Zhang… - Journal of Translational …, 2024 - Springer
Pediatric lymphoepithelioma-like carcinoma (pLELC) is a rare neoplasm with unclear
prognosis, genome, and tumor microenvironment. Our study aims to elucidate its genomic …

Self-supplying Cu 2+ and H 2 O 2 synergistically enhancing disulfiram-mediated melanoma chemotherapy

Y Gao, X Cai, W Zou, X Tang, L Jiang, J Hao, Y Zheng… - RSC …, 2024 - pubs.rsc.org
Disulfiram (DSF) can target and kill cancer cells by disrupting cellular degradation of
extruded proteins and has therefore received particular attention for its tumor …

[HTML][HTML] A Multi-Omics Prognostic Model Capturing Tumor Stemness and the Immune Microenvironment in Clear Cell Renal Cell Carcinoma

B Xiong, W Liu, Y Liu, T Chen, A Lin, J Song, L Qu… - Biomedicines, 2024 - mdpi.com
Background: Cancer stem-like cells (CSCs), a distinct subset recognized for their stem cell-
like abilities, are intimately linked to the resistance to radiotherapy, metastatic behaviors …

Paediatric Personalized Research Network Switzerland (SwissPedHealth): a joint paediatric national data stream

R Mozun, FN Belle, A Agostini, MR Baumgartner… - BMJ open, 2024 - bmjopen.bmj.com
Introduction Children represent a large and vulnerable patient group. However, the
evidence base for most paediatric diagnostic and therapeutic procedures remains limited or …