Exploring the evidence for epigenetic regulation of environmental influences on child health across generations
CV Breton, R Landon, LG Kahn, MB Enlow… - Communications …, 2021 - nature.com
Environmental exposures, psychosocial stressors and nutrition are all potentially important
influences that may impact health outcomes directly or via interactions with the genome or …
influences that may impact health outcomes directly or via interactions with the genome or …
Genetics and epigenetics in asthma
P Ntontsi, A Photiades, E Zervas, G Xanthou… - International Journal of …, 2021 - mdpi.com
Asthma is one of the most common respiratory disease that affects both children and adults
worldwide, with diverse phenotypes and underlying pathogenetic mechanisms poorly …
worldwide, with diverse phenotypes and underlying pathogenetic mechanisms poorly …
The LifeCycle Project-EU Child Cohort Network: a federated analysis infrastructure and harmonized data of more than 250,000 children and parents
VWV Jaddoe, JF Felix, AMN Andersen… - European journal of …, 2020 - Springer
Early life is an important window of opportunity to improve health across the full lifecycle. An
accumulating body of evidence suggests that exposure to adverse stressors during early life …
accumulating body of evidence suggests that exposure to adverse stressors during early life …
Decoding the genetic and epigenetic basis of asthma
Asthma is a complex and heterogeneous chronic inflammatory disease of the airways.
Alongside environmental factors, asthma susceptibility is strongly influenced by genetics …
Alongside environmental factors, asthma susceptibility is strongly influenced by genetics …
Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer's disease
DNA methylation differences in Alzheimer's disease (AD) have been reported. Here, we
conducted a meta-analysis of more than 1000 prefrontal cortex brain samples to prioritize …
conducted a meta-analysis of more than 1000 prefrontal cortex brain samples to prioritize …
Omics technologies in allergy and asthma research: An EAACI position paper
U Radzikowska, K Baerenfaller, JA Cornejo‐Garcia… - Allergy, 2022 - Wiley Online Library
Allergic diseases and asthma are heterogenous chronic inflammatory conditions with
several distinct complex endotypes. Both environmental and genetic factors can influence …
several distinct complex endotypes. Both environmental and genetic factors can influence …
Gene‐environment interactions in childhood asthma revisited; expanding the interaction concept
N Hernandez‐Pacheco, M Kere… - Pediatric Allergy and …, 2022 - Wiley Online Library
Investigation of gene‐environment interactions (GxE) may provide important insights into the
gene regulatory framework in response to environmental factors of relevance for childhood …
gene regulatory framework in response to environmental factors of relevance for childhood …
Epigenome-wide meta-analysis of prenatal maternal stressful life events and newborn DNA methylation
A Kotsakis Ruehlmann, S Sammallahti… - Molecular …, 2023 - nature.com
Prenatal maternal stressful life events are associated with adverse neurodevelopmental
outcomes in offspring. Biological mechanisms underlying these associations are largely …
outcomes in offspring. Biological mechanisms underlying these associations are largely …
Epigenome-wide association analysis of infant bronchiolitis severity: a multicenter prospective cohort study
Z Zhu, Y Li, RJ Freishtat, JC Celedón… - Nature …, 2023 - nature.com
Bronchiolitis is the most common lower respiratory infection in infants, yet its pathobiology
remains unclear. Here we present blood DNA methylation data from 625 infants hospitalized …
remains unclear. Here we present blood DNA methylation data from 625 infants hospitalized …
Recent findings in the genetics and epigenetics of asthma and allergy
M Kabesch, J Tost - Seminars in immunopathology, 2020 - Springer
In asthma and allergy genetics, a trend towards a few main topics developed over the last 2
years. First, a number of studies have been published recently which focus on overlapping …
years. First, a number of studies have been published recently which focus on overlapping …