Tuberculosis, a disease of poverty is a communicable infection with a reasonably high
mortality rate worldwide. 10 Million new cases of TB were reported with approx 1.4 million …

Oxadiazole is a five-membered heterocyclic compound containing two nitrogen atoms and
one oxygen atom. The 1, 3, 4-oxadiazole and 1, 2, 4-oxadiazole have favourable physical …

Abstract A library of 1, 2, 3-triazole incorporated thiazolylcarboxylate derivatives (7a-q) and
(8a-j) were synthesized and evaluated for their in-vitro antitubercular activity against …

In the present study, we have reported the synthesis of novel isoniazid-triazole derivatives
(4a-r), via the click chemistry approach. The synthesized isoniazid-triazole derivatives have …

triazole is a five-member nitrogen-containing heterocyclic compound with diverse biological
activities. A number of 1, 2, 3-triazole-containing FDA-approved drugs are available on the …

Antituberculosis drugs, mostly developed over 60 years ago, combined with a poorly
effective vaccine, have failed to eradicate tuberculosis. More worryingly, multiresistant …

Mycobacterium tuberculosis (Mtb) has numerous cell wall and non‐cell wall mediated
receptors for drug action, of which cell wall mediated targets were found to be more …

Zika virus (ZIKV) is a mosquito-borne virus belonging to the Flaviviridae family and is
responsible for an exanthematous disease and severe neurological manifestations, such as …

In a quest to discover new antimalarial and antitubercular drugs, we have designed and
synthesized a series of novel triazole–quinazolinone hybrids. The in vitro screening of the …

Visceral leishmaniasis (VL), caused by protozoa of the genus Leishmania, remains a
significant public health concern due to its potentially lethal nature if untreated. Current …