Macrophages are dynamic cells that play critical roles in the induction and resolution of
sterile inflammation. In this review, we will compile and interpret recent findings on the …

Lung macrophages play important roles in the maintenance of homeostasis, pathogen
clearance and immune regulation. The different types of pulmonary macrophages and their …

Disrupted development of the gut microbiota is a contributing cause of childhood
malnutrition. Bifidobacterium longum subspecies infantis is a prominent early colonizer of …

Highlights•Type I IFN is implicated in SLE pathogenesis by multiple lines of evidence,
including genetics and induction of SLE by IFN treatment.•Nucleic-acid sensing pathways …

Efficient inflammation resolution is important not only for the termination of the inflammatory
response but also for the restoration of tissue integrity. An integral process to resolution of …

Dysregulated immune responses against the SARS-CoV-2 virus are instrumental in severe
COVID-19. However, the immune signatures associated with immunopathology are poorly …

Acute inflammation is a localized and self-limited innate host-defense mechanism against
invading pathogens and tissue injury. Neutrophils, the most abundant immune cells in …

Neutrophil‐centred inflammation and flawed clearance of neutrophils cause and exuberate
multiple pathological conditions. These most abundant leukocytes exhibit very high daily …

The peritoneal cavity is a fluid filled space that holds most of the abdominal organs,
including the omentum, a visceral adipose tissue that contains milky spots or clusters of …

Dendritic cells (DC) are specialized mononuclear phagocytes that link innate and adaptive
immunity. They comprise two principal subsets: plasmacytoid DC (pDC) and conventional …