Owing to the efficacy in reducing pain and inflammation, non-steroidal anti-inflammatory
drugs (NSAIDs) are amongst the most popularly used medicines confirming their position in …

The gastrointestinal tract consists of an enormous surface area that is optimized to efficiently
absorb nutrients, water, and electrolytes from food. At the same time, it needs to provide a …

Nonsteroidal anti-inflammatory drugs (NSAIDs) can damage the gastrointestinal tract,
causing widespread morbidity and mortality. Although mechanisms of damage involve the …

Keeping in view the involvement of inflammation in the pathogenesis of several diseases
including cancer, diabetes, neurodegenerative disorders and rheumatoid arthritis, herein …

Ibuprofen first came to market about 50 years ago and rapidly moved to over-the-counter
(OTC) sales. In April 2019, the National Agency for the Safety of Medicines and Health …

Nonsteroidal anti-inflammatory drugs (NSAID) s relieve pain, inflammation, and fever by
inhibiting the activity of cyclooxygenase isozymes (COX-1 and COX-2). Despite their clinical …

Background Systemic low-grade inflammation observed in diet-induced obesity has been
associated with dysbiosis and disturbance of intestinal homeostasis. This latter relies on an …

The intestinal milieu is astonishingly complex and home to a constantly changing mixture of
small and large molecules, along with an abundance of bacteria, viral particles, and …

Inflammatory Bowel Disease (IBD) represents a group of idiopathic disorders characterized
by chronic or recurring inflammation of the gastrointestinal tract. While the exact etiology of …

For more than three decades, acetaminophen (INN, paracetamol) has been claimed to be
devoid of significant inhibition of peripheral prostanoids. Meanwhile, attempts to explain its …