Cancer cachexia is a multifactorial syndrome characterized by a progressive loss of skeletal
muscle mass, along with adipose tissue wasting, systemic inflammation and other metabolic …

Only in recent years, thanks to a precision medicine-based approach, have treatments
tailored to the sex of each patient emerged in clinical trials. In this regard, both striated …

Cachexia is a complex multifactorial syndrome, characterized by loss of skeletal muscle and
fat mass, which affects the majority of advanced cancer patients and is associated with poor …

Alterations in amino acid and protein metabolism—particularly in skeletal muscle—are a key
feature of cancer that contributes to the cachexia syndrome. Thus, skeletal muscle protein …

Significant loss of muscle mass may occur in cachexia and sarcopenia, which are major
causes of mortality and disability. Cachexia represents a complex multi-organ syndrome …

Cancer cachexia is a multifactorial metabolic syndrome characterized by the rapid loss of
skeletal muscle mass with or without the loss of fat mass. Nearly 50–80% of all cancer …

Cachexia is a multifactorial paraneoplastic syndrome commonly associated with advanced
stages of cancer. Cachexia is responsible for poor responses to antitumoral treatment and …

MicroRNAs (miRNAs) are small, non-coding RNA molecules that are mainly involved in
translational repression by binding to specific messenger RNAs. Recently, miRNAs have …

Body weight loss, mostly due to the wasting of skeletal muscle and adipose tissue, is the
hallmark of the so-called cachexia syndrome. Cachexia is associated with several acute and …

Cachexia is a complex metabolic syndrome that promotes great weight loss, with marked
muscle mass wasting. In the last years, many efforts have been directed to improve the …