As neonatal sepsis is a severe condition, there is a call for reliable biomarkers to
differentiate between infected and noninfected newborns. Although blood culture has been …

Innate immunity is the first barrier to fight off bacteria, and partly relies on the engagement of
the membrane coreceptor CD14. A product of cleavage of CD14, the soluble subtype of …

Introduction Sepsis, severe sepsis and septic shock are common conditions with high
mortality. Their early diagnosis in the Emergency Department (ED) is one of the keys to …

Importance Neonatal early-onset sepsis (EOS) is a severe disease, particularly in preterm
infants. Timely diagnosis can be challenging owing to unspecific presentation and …

Purpose Presepsin has recently emerged as a new useful sepsis marker, and our study is
focused on the usefulness of presepsin as earlier detection and monitoring biomarker for …

Objective Presepsin (soluble CD14 subtype) has been shown to be beneficial as a sepsis
marker in adults. Nevertheless, very few data are available in neonates. The aim of the …

BACKGROUND: Late-onset sepsis (LOS) is among the leading causes of morbidity and
mortality in preterm newborns, and currently available diagnostic tools are inadequate. The …

Background: Early-onset sepsis (EOS) is responsible for an important fraction of neonatal
morbidity and mortality all over the world. The aim of this study was to assess whether …

Presepsin is elevated in patients developing infections and increases in a severity-
dependent manner. We aimed to evaluate circulating values of this new biomarker in a …

Objective: One of the most challenging aspects in the management of neonates with late-
onset neonatal sepsis (LOS) is to make the diagnosis. Presepsin is a novel and promising …