Receptor activator of nuclear factor κB ligand and osteoprotegerin regulation of bone remodeling in health and disease

AE Kearns, S Khosla, PJ Kostenuik - Endocrine reviews, 2008 - academic.oup.com
Osteoclasts and osteoblasts dictate skeletal mass, structure, and strength via their respective
roles in resorbing and forming bone. Bone remodeling is a spatially coordinated lifelong …

The coming of age of virus-like particle vaccines

GT Jennings, MF Bachmann - 2008 - degruyter.com
Virus-like particles are supra-molecular assemblages, usually icosahedral or rod-like
structures. They incorporate key immunologic features of viruses which include repetitive …

Virus-like particles: flexible platforms for vaccine development

B Chackerian - Expert review of vaccines, 2007 - Taylor & Francis
Virus-like particles (VLPs) consist of viral structural proteins that, when overexpressed,
spontaneously self-assemble into particles that are antigenically indistinguishable from …

Osteoclasts, rheumatoid arthritis, and osteoimmunology

K Sato, H Takayanagi - Current opinion in rheumatology, 2006 - journals.lww.com
Osteoclasts, rheumatoid arthritis, and osteoimmunology : Current Opinion in Rheumatology
Osteoclasts, rheumatoid arthritis, and osteoimmunology : Current Opinion in Rheumatology Log …

Versatile virus-like particle carrier for epitope based vaccines

AC Tissot, R Renhofa, N Schmitz, I Cielens… - PloS one, 2010 - journals.plos.org
Background Recombinant proteins and in particular single domains or peptides are often
poorly immunogenic unless conjugated to a carrier protein. Virus-like-particles are a very …

Vaccination against IL‐17 suppresses autoimmune arthritis and encephalomyelitis

TA Röhn, GT Jennings, M Hernandez… - European journal of …, 2006 - Wiley Online Library
Interleukin 17 is a T cell‐derived cytokine that induces the release of pro‐inflammatory
mediators in a wide range of cell types. Recently, a subset of IL‐17‐producing T helper cells …

Development of virus-like particle technology from small highly symmetric to large complex virus-like particle structures

P Pushko, P Pumpens, E Grens - Intervirology, 2013 - karger.com
Virus-like particle (VLP) technology is a promising approach for the construction of novel
vaccines, diagnostic tools, and gene therapy vectors. Initially, VLPs were primarily derived …

The application of virus-like particles as vaccines and biological vehicles

D Yan, YQ Wei, HC Guo, SQ Sun - Applied microbiology and …, 2015 - Springer
Virus-like particles (VLPs) can be spontaneously self-assembled by viral structural proteins
under appropriate conditions in vitro while excluding the genetic material and potential …

Virus-like particles as an immunogenic platform for cancer vaccines

JC Caldeira, M Perrine, F Pericle, F Cavallo - Viruses, 2020 - mdpi.com
Virus-like particles (VLP) spontaneously assemble from viral structural proteins. They are
naturally biocompatible and non-infectious. VLP can serve as a platform for many potential …

Immunogenic display of diverse peptides on virus-like particles of RNA phage MS2

DS Peabody, B Manifold-Wheeler, A Medford… - Journal of molecular …, 2008 - Elsevier
The high level of immunogenicity of peptides displayed in dense repetitive arrays on virus-
like particles makes recombinant VLPs promising vaccine carriers. Here, we describe a …