Developing therapeutic approaches for twenty-first-century emerging infectious viral diseases

RM Meganck, RS Baric - Nature medicine, 2021 - nature.com
The twenty-first century has already recorded more than ten major epidemic or pandemic
virus emergence events, including the ongoing and devastating coronavirus disease 2019 …

Developing a direct acting, orally available antiviral agent in a pandemic: the evolution of molnupiravir as a potential treatment for COVID-19

GR Painter, MG Natchus, O Cohen, W Holman… - Current opinion in …, 2021 - Elsevier
Highlights•Molnupiravir is a broad acting, oral antiviral versus SARS-CoV-2, flu, Ebola and
others.•Clinical development was greatly accelerated in response to the COVID19 …

A framework for automated scalable designation of viral pathogen lineages from genomic data

J McBroome, A de Bernardi Schneider, C Roemer… - Nature …, 2024 - nature.com
Pathogen lineage nomenclature systems are a key component of effective communication
and collaboration for researchers and public health workers. Since February 2021, the …

Dogs (Canis familiaris) as Sentinels for Human Infectious Disease and Application to Canadian Populations: A Systematic Review

NH Bowser, NE Anderson - Veterinary sciences, 2018 - mdpi.com
In a world where climate change, vector expansion, human activity, and pathogen dispersal
do not respect boundaries, the human–animal–pathogen interface has become less …

Entry receptor LDLRAD3 is required for Venezuelan equine encephalitis virus peripheral infection and neurotropism leading to pathogenesis in mice

NM Kafai, H Janova, MD Cain, Y Alippe, S Muraro… - Cell reports, 2023 - cell.com
Venezuelan equine encephalitis virus (VEEV) is an encephalitic alphavirus responsible for
epidemics of neurological disease across the Americas. Low-density lipoprotein receptor …

Distinct cellular tropism and immune responses to alphavirus infection

NM Kafai, MS Diamond, JM Fox - Annual review of immunology, 2022 - annualreviews.org
Alphaviruses are emerging and reemerging viruses that cause disease syndromes ranging
from incapacitating arthritis to potentially fatal encephalitis. While infection by arthritogenic …

Introduction and dispersal of sindbis virus from Central Africa to Europe

J Ling, T Smura, JO Lundström, JHO Pettersson… - Journal of …, 2019 - Am Soc Microbiol
Bird-hosted viruses have the potential to be transported over large areas of the world and to
be transmitted in distant geographical regions. Sindbis virus (SINV) is a mosquito-borne …

Everglades virus: an underrecognized disease-causing subtype of Venezuelan equine encephalitis virus endemic to Florida, USA

ND Burkett-Cadena, D Fish, S Weaver… - Journal of medical …, 2023 - academic.oup.com
Everglades virus (EVEV) is subtype II of the Venezuelan equine encephalitis virus (VEEV)
complex (Togaviridae: Alphavirus), endemic to Florida, USA. EVEV belongs to a clade that …

Venezuelan equine encephalitis virus: the problem is not over for tropical America

C Guzmán-Terán, A Calderón-Rangel… - Annals of clinical …, 2020 - Springer
The equine encephalitis viruses, Venezuelan (VEEV), East (EEEV) and West (WEEV),
belong to the genus alphavirus, family Togaviridae and still represent a threat for human and …

[HTML][HTML] Codon usage bias of Venezuelan equine encephalitis virus and its host adaption

H Wang, S Liu, Y Lv, W Wei - Virus research, 2023 - Elsevier
Venezuelan equine encephalitis virus (VEEV) is an emerging zoonotic virus in the
alphavirus genus. It can be transmitted to humans due to spillover from equid-mosquito …