The degenerative ataxias comprise a heterogeneous group of inherited and acquired
disorders that are characterized by a progressive cerebellar syndrome, frequently in …

The advent of next-generation technology has significantly advanced the implementation
and delivery of Deep Brain Stimulation (DBS) for Essential Tremor (ET), yet controversies …

Frontal circuits play a critical role in motor, cognitive and affective processing, and their
dysfunction may result in a variety of brain disorders. However, exactly which frontal …

Objective This study was undertaken to describe relationships between electrode
localization and motor outcomes from the subthalamic nucleus (STN) deep brain stimulation …

Spatial normalization—the process of mapping subject brain images to an average template
brain—has evolved over the last 20+ years into a reliable method that facilitates the …

Background Deep brain stimulation (DBS) is a promising treatment option for treatment-
refractory obsessive-compulsive disorder (OCD). Several stimulation targets have been …

Introduction Obsessive-compulsive disorder (OCD) is clinically and pathologically
heterogenous, with symptoms often refractory to first-line treatments. Deep brain stimulation …

A major challenge in Parkinson's disease is the variability in symptoms and rates of
progression, underpinned by heterogeneity of pathological processes. Biomarkers are …

Objective Here, we report a retrospective, single‐center experience with a novel deep brain
stimulation (DBS) device capable of chronic local field potential (LFP) recording in drug …

Abstract Deep Brain Stimulation can improve tremor, bradykinesia, rigidity, and axial
symptoms in patients with Parkinson's disease. Potentially, improving each symptom may …