Significance of mechanical loading in bone fracture healing, bone regeneration, and vascularization

Q Ma, Z Miri, HJ Haugen… - Journal of Tissue …, 2023 - journals.sagepub.com
In 1892, JL Wolff proposed that bone could respond to mechanical and biophysical stimuli
as a dynamic organ. This theory presents a unique opportunity for investigations on bone …

[HTML][HTML] Effects of mechanical stress stimulation on function and expression mechanism of osteoblasts

P Liu, J Tu, W Wang, Z Li, Y Li, X Yu… - … in Bioengineering and …, 2022 - frontiersin.org
Osteoclasts and osteoblasts play a major role in bone tissue homeostasis. The homeostasis
and integrity of bone tissue are maintained by ensuring a balance between osteoclastic and …

3D-Printing biodegradable PU/PAAM/gel hydrogel scaffold with high flexibility and self-adaptibility to irregular defects for nonload-bearing bone regeneration

M He, Y Hou, C Zhu, M He, Y Jiang, G Feng… - Bioconjugate …, 2021 - ACS Publications
A three-dimensional (3D) printed biodegradable hydrogel scaffold with a strong self-
expanding ability to conform to the contour of irregular bone defects and be closely adjacent …

[HTML][HTML] An evaluation of different 3D cultivation models on expression profiles of human periodontal ligament fibroblasts with compressive strain

A Schröder, R Schöniger, J Oeldemann… - International journal of …, 2022 - mdpi.com
The effects of compressive strain during orthodontic treatment on gene expression profiles of
periodontal ligament fibroblasts (PDLFs) have mostly been studied in 2D cell culture …

Channeling force in the brain: mechanosensitive ion channels choreograph mechanics and malignancies

A Momin, S Bahrampour, HK Min, X Chen… - Trends in …, 2021 - cell.com
Force is everywhere. Through cell-intrinsic activities and interactions with the
microenvironment, cells generate, transmit, and sense mechanical forces, such as …

The role of physical forces in osteoclastogenesis

Q Ma, Z Ma, M Liang, F Luo, J Xu… - Journal of Cellular …, 2019 - Wiley Online Library
The movements of life at every level from organs, tissues, cells to sub‐cells, are all
conducted in certain physical environments. In the human body, skeletal tissue among all …

On the biomechanical properties of osteosarcoma cells and their environment

DA Müller, U Silvan - The International journal of developmental biology, 2019 - zora.uzh.ch
Although rare among the general population, bone malignancies have a high rate of
incidence among children and adolescents and are associated with high mortality rates …

[HTML][HTML] Contact stress distribution after unilateral condylar fracture with angulation of the fractured part: A finite element model study

LML Helmer, C Klop, F Lobbezoo, J de Lange… - Journal of …, 2023 - Elsevier
After a fracture of the condyle, the head of the condyle is often pulled inwards, which causes
the fractured part to angulate medially. This change can cause a disbalance in the …

Human Tooth Enamel, a Sophisticated Material

EF Brès, J Reyes-Gasga, J Hemmerlé - … Matrix Biomineralization of Dental …, 2021 - Springer
Human teeth are sophisticated materials that we use every day. We attempt here to describe
how the mechanical and chemical properties (resistance to carious dissolution), are …

[HTML][HTML] LAPTM5 is transactivated by RUNX2 and involved in RANKL trafficking in osteoblastic cells

YM Geng, CX Liu, WY Lu, P Liu… - Molecular …, 2019 - spandidos-publications.com
The present study aimed to investigate the role of lysosomal‑associated transmembrane
protein 5 (LAPTM5) in osteoclast differentiation induced by osteoblasts. The results …