The limited efficacy of benznidazole (Bz) indicated by failures of current Phase II clinical
trials emphasizes the urgent need to identify new drugs with improved safety and efficacy for …

Chemical conversion of the extract of natural resources is a very attractive way to expand the
chemical space to discover bioactive compounds. In order to search for new medicines to …

African trypanosomes cause diseases in humans and livestock. Human African
trypanosomiasis is caused by Trypanosoma brucei rhodesiense and T. b. gambiense …

The protozoan parasite Leishmania causes leishmaniasis; a spectrum of diseases of which
there are an estimated 1 million new cases each year. Current treatments are toxic …

Artemisia sieversiana is an annual herbaceous plant distributed throughout Central and
East Eurasia and is regarded as an undesirable forage plant in Mongolia. It affects livestock …

Fomitopsis officinalis is a medicinal fungus, known as 'Agarikon', and is used traditionally in
the treatment of asthma and rheumatism in Mongolia. The investigation of the chemical …

Eleven 2, 5-diphenyloxazole derivatives (1–11), together with six known isoflavonoid
derivatives, were isolated from the roots of Oxytropis lanata. The 2, 5-diphenyloxazole (1) …

African trypanosomiasis is a major problem for human and animal health in endemic
countries, where it threatens millions of people and affects economic development. New …

The occurrence and bioactivities of marine-derived fungi are evaluated in this paper. A total
of 16 morphospecies of marine-derived fungi (MDF) were isolated from four host …

The Asteraceae family is a promising source of bioactive compounds, such as the famous
Asteraceae plants Tanacetum cinerariifolium (pyrethrin) and Artemisia annua (artemisinin) …