In recent years, polymeric micelles have been extensively utilized in pre-clinical studies for
delivering poorly soluble chemotherapeutic agents in cancer. Polymeric micelles are formed …

Poloxamers, also called Pluronic, belong to a unique class of synthetic tri-block copolymers
containing central hydrophobic chains of poly (propylene oxide) sandwiched between two …

Background: Nanotechnology is gaining significant attention worldwide for cancer treatment.
Nanobiotechnology encourages the combination of diagnostics with therapeutics, which is a …

Block co-polymeric micelles receive increased attention due to their ability to load
therapeutics, deliver the cargo to the site of action, improve the pharmacokinetic of the …

During the past few decades, polymeric micelles have raised special attention as novel
nano-sized drug delivery systems for optimizing the treatment and diagnosis of numerous …

Though much progress has been made in drug delivery systems, the design of a suitable
carrier for the delivery of hydrophobic drugs is still a major challenge for researchers. The …

Most of the administered anti-cancer drugs are hydrophobic in nature and are known to
have poor water solubility, short residence time, rapid clearance from the body and systemic …

Multidrug resistance (MDR) of cancer is a persistent problem in chemotherapy. Scientists
have considered the overexpressed efflux transporters responsible for MDR and …

A type of pH-responsive nano multi-drug delivery systems (nano-MDDSs) with uniform
particle size (100±13 nm) and excellent monodispersity was developed by in situ co-self …

Background: Intervertebral disc (IVD) degeneration is a common degenerative disease that
can lead to collapse or herniation of the nucleus pulposus (NP) and result in radiculopathy …