History of the development of antifungal azoles: A review on structures, SAR, and mechanism of action
With the increasing risk of invasive and life threating fungal infections, there is now a great
concern regarding the lower discovery rate of antifungal drugs in comparison to …
concern regarding the lower discovery rate of antifungal drugs in comparison to …
[HTML][HTML] Preparation and antimicrobial activity of chitosan and its derivatives: A concise review
LG Confederat, CG Tuchilus, M Dragan, M Sha'at… - Molecules, 2021 - mdpi.com
Despite the advantages presented by synthetic polymers such as strength and durability, the
lack of biodegradability associated with the persistence in the environment for a long time …
lack of biodegradability associated with the persistence in the environment for a long time …
[HTML][HTML] Current antimycotics, new prospects, and future approaches to antifungal therapy
G Wall, JL Lopez-Ribot - Antibiotics, 2020 - mdpi.com
Fungal infections represent an increasing threat to a growing number of immune-and
medically compromised patients. Fungi are eukaryotic organisms and, as such, there is a …
medically compromised patients. Fungi are eukaryotic organisms and, as such, there is a …
[HTML][HTML] Recent advances in polymeric nanoparticle-encapsulated drugs against intracellular infections
A Sánchez, SP Mejía, J Orozco - Molecules, 2020 - mdpi.com
Polymeric nanocarriers (PNs) have demonstrated to be a promising alternative to treat
intracellular infections. They have outstanding performance in delivering antimicrobials …
intracellular infections. They have outstanding performance in delivering antimicrobials …
[HTML][HTML] Antifungals and drug resistance
Definition Antifungal drugs prevent topical or invasive fungal infections (mycoses) either by
stopping growth of fungi (termed fungistatic) or by killing the fungal cells (termed fungicidal) …
stopping growth of fungi (termed fungistatic) or by killing the fungal cells (termed fungicidal) …
Metal incorporated sulfonamides as promising multidrug targets: Combined enzyme inhibitory, antimicrobial, antioxidant and theoretical exploration
In this report, new sulfonamide based ligands (L 1)-(L 3) from 4-amino-N-(pyrimidin-2-yl)
benzene-1-sulfonamide are synthesized and branded on the basis of their physical …
benzene-1-sulfonamide are synthesized and branded on the basis of their physical …
Cinnamaldehyde incorporated gellan/PVA electrospun nanofibers for eradicating Candida biofilm
Immunocompromised patients encounter fungal infections more frequently than healthy
individuals. Conventional drugs associated health risk and resistance, portrayed fungal …
individuals. Conventional drugs associated health risk and resistance, portrayed fungal …
[HTML][HTML] α-Terpinyl Acetate: Occurrence in Essential Oils Bearing Thymus pulegioides, Phytotoxicity, and Antimicrobial Effects
V Vaičiulytė, K Ložienė, J Švedienė, V Raudonienė… - Molecules, 2021 - mdpi.com
The aim of this study was to evaluate occurrence of T. pulegioides α-terpinyl acetate
chemotype, as source of natural origin α-terpinyl acetate, to determine its phytotoxic and …
chemotype, as source of natural origin α-terpinyl acetate, to determine its phytotoxic and …
[HTML][HTML] COVID-19-associated fungal infections: an urgent need for alternative therapeutic approach?
Secondary fungal infections may complicate the clinical course of patients affected by viral
respiratory diseases, especially those admitted to intensive care unit. Hospitalized COVID …
respiratory diseases, especially those admitted to intensive care unit. Hospitalized COVID …
[HTML][HTML] Post-translational modifications drive success and failure of fungal–host interactions
C Retanal, B Ball, J Geddes-McAlister - Journal of Fungi, 2021 - mdpi.com
Post-translational modifications (PTMs) change the structure and function of proteins and
regulate a diverse array of biological processes. Fungal pathogens rely on PTMs to …
regulate a diverse array of biological processes. Fungal pathogens rely on PTMs to …