The Rickettsiales are a group of obligate intracellular vector-borne Gram-negative bacteria
that include many organisms of clinical and agricultural importance, including Anaplasma …

Ticks are hematophagous ectoparasites capable of transmitting multiple human pathogens.
Environmental changes have supported the expansion of ticks into new geographical areas …

The evolution of obligate host-association of bacterial symbionts and pathogens remains
poorly understood. The Rickettsiales are an alphaproteobacterial order of obligate …

The most common intracellular symbiont on the planet—Wolbachia pipientis—is infamous
largely for the reproductive manipulations induced in its host. However, more recent …

Bacterial symbionts are integral to the health and homeostasis of invertebrate hosts.
Notably, members of the Rickettsiales genus Wolbachia influence several aspects of the …

Members of the bacterial genus Rickettsia were originally identified as causative agents of
vector-borne diseases in mammals. However, many Rickettsia species are arthropod …

Rickettsioses are among the oldest known infectious diseases. In spite of this, and of the
extensive research carried out, many aspects of the biology and epidemiology of tick-borne …

Deazaguanine modifications play multifaceted roles in the molecular biology of DNA and
tRNA, shaping diverse yet essential biological processes, including the nuanced fine-tuning …

Recent discoveries of basal extracellular Rickettsiales have illuminated divergent
evolutionary paths to host dependency in later-evolving lineages. Family Rickettsiaceae …

Viruses generally are defined as lacking the fundamental properties of living organisms in
that they do not harbor an energy metabolism system or protein synthesis machinery …