This review focuses on the attachment of polymer brushes to polymeric biomaterial
substrates by chemical surface modification methods for biomedical applications. In the first …

Cardiovascular diseases, especially ones involving narrowed or blocked blood vessels with
diameters smaller than 6 millimeters, are the leading cause of death globally. Vascular grafts …

Mechanistic understanding of the topological cues delivered by biomaterials in promotion of
oriented tissue regeneration (eg., peripheral nerve regrowth) remains largely elusive. Here …

There is a lack in clinically-suitable vascular grafts. Biotubes, prepared using in vivo tissue
engineering, show potential for vascular regeneration. However, their mechanical strength is …

Bone regeneration is largely affected by mechanical cues in the surrounding
microenvironment, and natural new bone formation is an uninterrupted stiffening …

Mimicking complex structures of natural blood vessels and constructing vascular networks in
tissue engineering scaffolds are still challenging now. Herein we demonstrate a new and …

Small-diameter vascular grafts (SDVGs) are urgently required for clinical applications.
Constructing vascular grafts mimicking the defining features of native arteries is a promising …

Native arteries contain a distinctive intima‐media composed of organized elastin and an
adventitia containing mature collagen fibrils. In contrast, implanted biodegradable small …

In situ tissue engineering that uses resorbable synthetic heart valve scaffolds is an
affordable and practical approach for heart valve replacement; therefore, it is attractive for …

Cardiovascular devices have been widely applied in the clinical treatment of cardiovascular
diseases. However, poor hemocompatibility and slow endothelialization on their surface still …