Annual research review: Towards a deeper understanding of nature and nurture: Combining family‐based quasi‐experimental methods with genomic data

TA McAdams, R Cheesman… - Journal of Child …, 2023 - Wiley Online Library
Distinguishing between the effects of nature and nurture constitutes a major research goal
for those interested in understanding human development. It is known, for example, that …

A biopsychosocial approach to processes and pathways in the development of overweight and obesity in childhood: Insights from developmental theory and research

CG Russell, A Russell - Obesity reviews, 2019 - Wiley Online Library
Childhood obesity has reached alarming proportions in many countries. There is consensus
that both biological (especially genetic) and environmental (including psychosocial) factors …

[HTML][HTML] Comparing within-and between-family polygenic score prediction

S Selzam, SJ Ritchie, JB Pingault, CA Reynolds… - The American Journal of …, 2019 - cell.com
Polygenic scores are a popular tool for prediction of complex traits. However, prediction
estimates in samples of unrelated participants can include effects of population stratification …

Evaluation of polygenic prediction methodology within a reference-standardized framework

O Pain, KP Glanville, SP Hagenaars, S Selzam… - PLoS …, 2021 - journals.plos.org
The predictive utility of polygenic scores is increasing, and many polygenic scoring methods
are available, but it is unclear which method performs best. This study evaluates the …

Feeding practices and parenting: A pathway to child health and family happiness

LA Daniels - Annals of Nutrition and Metabolism, 2019 - karger.com
Feeding and parenting are inextricably linked. The complex bidirectional interactions
between parent feeding practices and child eating behaviour shape the early feeding …

Genetic associations between non-cognitive skills and academic achievement over development

M Malanchini, AG Allegrini, MG Nivard, P Biroli… - Nature human …, 2024 - nature.com
Non-cognitive skills, such as motivation and self-regulation, are partly heritable and predict
academic achievement beyond cognitive skills. However, how the relationship between non …

Twins early development study: A genetically sensitive investigation into behavioral and cognitive development from infancy to emerging adulthood

K Rimfeld, M Malanchini, T Spargo… - Twin Research and …, 2019 - cambridge.org
The Twins Early Development Study (TEDS) is a longitudinal twin study that recruited over
16,000 twin-pairs born between 1994 and 1996 in England and Wales through national birth …

Correlation between family history and characteristics of breast cancer

L Liu, X Hao, Z Song, X Zhi, S Zhang, J Zhang - Scientific reports, 2021 - nature.com
Family history is a major risk factor for breast cancer; approximately 5–10% cases of breast
cancer are associated with a family history. Herein, we investigated the link between family …

Gene–environment interaction using polygenic scores: Do polygenic scores for psychopathology moderate predictions from environmental risk to behavior problems?

R Plomin, A Gidziela, M Malanchini… - Development and …, 2022 - cambridge.org
The DNA revolution has energized research on interactions between genes and
environments (GxE) by creating indices of G (polygenic scores) that are powerful predictors …

Twins and causal inference: leveraging nature's experiment

TA McAdams, FV Rijsdijk… - Cold Spring …, 2021 - perspectivesinmedicine.cshlp.org
In this review, we discuss how samples comprising monozygotic and dizygotic twin pairs can
be used for the purpose of strengthening causal inference by controlling for shared …