Nitric oxide plays an important role in various biological processes, such as
neurotransmission, blood pressure control, immunological responses, and antioxidant …

Endothelial dysfunction is the hallmark of hypertension, which is a multifactorial disorder. In
the cardiovascular system reactive oxygen species play a pivotal role in controlling the …

Mounting evidence indicates that structural and functional vascular changes associated with
two-kidney, one-clip (2K-1C) hypertension result, at least in part, from altered activity of …

New Findings What is the central question of this study? Is the near‐infrared spectroscopy‐
derived measure of tissue oxygen saturation () reperfusion slope sensitive to a range of …

Background and aims Increased activity of matrix metalloproteinase (MMP)-2 is observed in
aortas of different models of hypertension, and its activation is directly mediated by oxidative …

Background Cardiovascular disease (CVD) is associated with impairments in microvascular
responsiveness. Therefore, reliably assessing microvascular function is clinically relevant …

Introduction: Hypertension is a leading cause of morbidity and mortality worldwide. A major
pathophysiological factor contributing to hypertension is reduced nitric oxide (NO) …

Ellagic acid is described as having antioxidant and antiproliferative properties. Hence, it was
hypothesized that ellagic acid could improve cardiovascular damage caused by …

Endothelial dysfunction and consequent vasoconstriction are a common condition in
patients with hypertension and other cardiovascular diseases. Endothelial cells produce and …

Aims The uremic toxin indoxyl sulfate (IS) was reported to be the cause of cardiovascular
disease associated with chronic kidney disease. Therefore, we evaluated the direct …