Neurobiology of bipolar disorders: a review of genetic components, signaling pathways, biochemical changes, and neuroimaging findings

G Scaini, SS Valvassori, AP Diaz, CN Lima… - Brazilian Journal of …, 2020 - SciELO Brasil
Bipolar disorder (BD) is a chronic mental illness characterized by changes in mood that
alternate between mania and hypomania or between depression and mixed states, often …

Accelerated aging in bipolar disorder: A comprehensive review of molecular findings and their clinical implications

GR Fries, MJ Zamzow, T Andrews, O Pink… - Neuroscience & …, 2020 - Elsevier
Bipolar disorder (BD) has been associated with clinical signs of accelerated aging, which
potentially underlies its association with several age-related medical conditions, such as …

Cognition in older adults with bipolar disorder: an ISBD task force systematic review and meta‐analysis based on a comprehensive neuropsychological assessment

L Montejo, C Torrent, E Jimenez… - Bipolar …, 2022 - Wiley Online Library
Objectives We aim to characterize the cognitive performance in euthymic older adults with
bipolar disorder (OABD) through a comprehensive neuropsychological assessment to …

Interactive relationships of Type 2 diabetes and bipolar disorder with cognition: evidence of putative premature cognitive ageing in the UK Biobank Cohort

E Ringin, DW Dunstan, RS McIntyre, M Berk… - …, 2023 - nature.com
Abstract Type 2 diabetes (T2D) is disproportionately prevalent in bipolar disorder (BD) and
is associated with cognitive deficits in psychiatrically healthy cohorts. Whether there is an …

A cross-sectional study of cognitive performance in bipolar disorder across the lifespan: the cog-BD project

BDM Jones, BS Fernandes, MI Husain, A Ortiz… - Psychological …, 2023 - cambridge.org
BackgroundNeuroprogressive models of the trajectory of cognitive dysfunction in patients
with bipolar disorder (BD) have been proposed. However, few studies have explored the …

Differential associations of mentally-active and passive sedentary behaviours and physical activity with putative cognitive decline in healthy individuals and those with …

E Ringin, DW Dunstan, RS McIntyre, N Owen… - Mental Health and …, 2023 - Elsevier
Objective Physical activity confers protection against age-related cognitive dysfunction, but
less is known about whether cognition is impacted by sedentary behaviour, specifically its …

The interactions between vitamin D and neurofilament light chain levels on cognitive domains in bipolar disorder

WY Chen, MC Huang, CC Chiu, YC Cheng, CJ Kuo… - BJPsych …, 2022 - cambridge.org
Background Bipolar disorder is a chronic mental disorder related to cognitive deficits. Low
serum vitamin D levels are significantly associated with compromised cognition in …

Aging in bipolar disorder: Cognitive performance and clinical factors based on an adulthood-lifespan perspective

L Montejo, B Solé, E Jiménez, R Borràs… - Journal of Affective …, 2022 - Elsevier
Background The evolution of cognitive performance throughout the lifespan in bipolar
disorder (BD) is understudied. This cross-sectional study aims to describe the cognitive …

Bipolar disorder among patients diagnosed with frontotemporal dementia

MF Mendez, L Parand… - The Journal of …, 2020 - Am Neuropsych Assoc
Objective: Previous studies have documented manic and hypomanic symptoms in
behavioral variant frontotemporal dementia (bvFTD), suggesting a relationship between …

The heterogeneity of longitudinal cognitive decline in euthymic bipolar I disorder with clinical characteristics and functional outcomes

WY Chen, MC Huang, YC Lee, CE Chang… - Frontiers in …, 2021 - frontiersin.org
We characterized the heterogeneity and risk factors of cognitive decline in euthymic bipolar
disorder (BD), and their magnitude of associations with subjective daily functions. In this …