Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics

S Qin, W Xiao, C Zhou, Q Pu, X Deng, L Lan… - Signal transduction and …, 2022 - nature.com
Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen that
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …

Virulence Factors of Pseudomonas Aeruginosa and Antivirulence Strategies to Combat Its Drug Resistance

C Liao, X Huang, Q Wang, D Yao, W Lu - Frontiers in cellular and …, 2022 - frontiersin.org
Pseudomonas aeruginosa is an opportunistic pathogen causing nosocomial infections in
severely ill and immunocompromised patients. Ubiquitously disseminated in the …

A bottom-up view of antimicrobial resistance transmission in developing countries

OO Ikhimiukor, EE Odih, P Donado-Godoy… - Nature …, 2022 - nature.com
Antimicrobial resistance (AMR) is tracked most closely in clinical settings and high-income
countries. However, resistant organisms thrive globally and are transmitted to and from …

Nanomaterials with a photothermal effect for antibacterial activities: an overview

JW Xu, K Yao, ZK Xu - Nanoscale, 2019 - pubs.rsc.org
Nanomaterials and nanotechnologies have been expected to provide innovative platforms
for addressing antibacterial challenges, with potential to even deal with bacterial infections …

[HTML][HTML] Antibacterial and antifungal properties of resveratrol

M Vestergaard, H Ingmer - International Journal of Antimicrobial Agents, 2019 - Elsevier
Resveratrol is a naturally occurring polyphenolic antioxidant that has received massive
attention for its potential health benefits, including anticarcinogenesis, anti-aging and …

Antibiotic resistance and the MRSA problem

M Vestergaard, D Frees, H Ingmer - Microbiology spectrum, 2019 - Am Soc Microbiol
Staphylococcus aureus is capable of becoming resistant to all classes of antibiotics clinically
available and resistance can develop through de novo mutations in chromosomal genes or …

Quorum-sensing systems as targets for antivirulence therapy

T Defoirdt - Trends in microbiology, 2018 - cell.com
The development of novel therapies to control diseases caused by antibiotic-resistant
pathogens is one of the major challenges we are currently facing. Many important plant …

The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation

A Langdon, N Crook, G Dantas - Genome medicine, 2016 - Springer
The widespread use of antibiotics in the past 80 years has saved millions of human lives,
facilitated technological progress and killed incalculable numbers of microbes, both …

Clostridium difficile infection

WK Smits, D Lyras, DB Lacy, MH Wilcox… - Nature reviews Disease …, 2016 - nature.com
Infection of the colon with the Gram-positive bacterium Clostridium difficile is potentially life
threatening, especially in elderly people and in patients who have dysbiosis of the gut …

Bacterial outer membrane vesicles as a platform for biomedical applications: An update

M Li, H Zhou, C Yang, Y Wu, X Zhou, H Liu… - Journal of Controlled …, 2020 - Elsevier
Outer membrane vesicles (OMVs) are produced by Gram-negative bacteria both in vitro and
in vivo. OMVs are nano-sized spherical vehicles formed by lipid bilayer membranes and …