The production of harmful free radicals (H-FRs), especially those with oxygen or nitrogen
atoms, depends on both internal and environmental causes. The negative effects of H-FRs …

Abstract Background Kidney stones (KSs), in fact, have been considered one of the most
ancient and prevalent medical conditions that impact a significant number of human beings …

The hybridization of heterocycles presents a key opportunity to craft innovative multicyclic
compounds with enhanced biological activity. Coumarins, being broadly prevalent natural …

Phyto-coumarins demonstrate diverse biological actions, encompassing antiradical, anti-
inflammatory, oncolytic, monoamine oxidase B (MAOB) suppression, and antibacterial …

Cancer is regarded as a nightmare for humanity and a challenging task for medical
professionals. Twelve hydrides (2a-2l), made of trifunctionalized coumarin and various …

The large intestine is the final section of the gastrointestinal tract (GIT) and consists of the
caecum, colon, rectum, anal canal, and anus. The colon is the longest portion of the large …

In the literature, only two papers describe the synthesis of 3-mercaptocoumarins (3-MCMs)
without exploring their bioactivity. So, the novelty of this work is driven by the fact that it …

Among the most health-influencing threats, microbial infections and cancer have attracted a
mounting interest in the medical field. To face these threats, research is directed to improve …

Phytocoumarins exhibit a range of biological activities, including antibacterial, anti-
inflammatory, antiradical, oncolytic, and reduction of monoamine oxidase B effects. These …

Background: Esculetin, scientifically referred to as 6, 7-dihydroxycoumarin, functions as the
primary bioactive constituent found in Cortex Fraxini (commonly known as ash bark), an …