Accumulating evidence points to the causal role of triglyceride-rich lipoproteins and their
cholesterol-enriched remnants in atherogenesis. Genetic studies in particular have not only …

Lipids are insoluble in water and therefore cholesterol and triglycerides need to be
transported in association with proteins (ie, lipoproteins) in the bloodstream. Lipoproteins …

Cholesterol and triglycerides are insoluble in water and therefore these lipids must be
transported in association with proteins. Lipoproteins are complex particles with a central …

Orally administered drug entities have to survive the harsh gastrointestinal environment,
penetrate the enteric epithelia and circumvent hepatic metabolism before reaching the …

Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death and it has
been confirmed that increased low density lipoprotein cholesterol (LDL-C) is an …

An increased risk of cardiovascular disease, independent of conventional risk factors, is
present even at minor levels of renal impairment and is highest in patients with end-stage …

This article aims to highlight discoveries during the past 5 years regarding aspects of the
bioaccessibility of carotenoids and apo-carotenoids, their uptake by intestinal cells, and their …

Cholesterol is an essential component of cell barrier formation and signaling transduction
involved in many essential physiologic processes. For this reason, cholesterol metabolism …

Cardiovascular disease (CVD) is still the leading cause of death globally, and
atherosclerosis is the main pathological basis of CVDs. Low-density lipoprotein cholesterol …

Severe hypertriglyceridaemia is associated with pancreatitis and chronic pancreatitis-
induced diabetes. Familial chylomicronaemia syndrome (FCS) is a rare autosomal recessive …