Sex difference and benzene exposure: does it matter?

D Poli, P Mozzoni, S Pinelli, D Cavallo… - International Journal of …, 2022 - mdpi.com
Sex-related biological differences might lead to different effects in women and men when
they are exposed to risk factors. A scoping review was carried out to understand if sex could …

Urinary metabolites of multiple volatile organic compounds, oxidative stress biomarkers, and gestational diabetes mellitus: association analyses

S Chen, Y Wan, X Qian, A Wang, G Mahai, Y Li… - Science of The Total …, 2023 - Elsevier
Volatile organic compounds are ubiquitous in the environment, which may cause various
adverse health effects. The objectives of this study were to investigate associations of single …

Iron-dependent ferroptosis participated in benzene-induced anemia of inflammation through IRP1-DHODH-ALOX12 axis

W Zhang, J Wang, ZY Liu, L Zhang, J Jing… - Free Radical Biology …, 2022 - Elsevier
Benzene, a widely existing environmental pollutant, gives huge harm to the hematopoietic
system. Iron is one of the raw materials for the creation of blood cells, but the role of iron in …

Prenatal Pollutant Exposures and Hypothalamic Development: Early Life Disruption of Metabolic Programming

L Koshko, S Scofield, G Mor… - Frontiers in …, 2022 - frontiersin.org
Environmental contaminants in ambient air pollution pose a serious risk to long-term
metabolic health. Strong evidence shows that prenatal exposure to pollutants can …

Adult-Onset Transcriptomic Effects of Developmental Exposure to Benzene in Zebrafish (Danio rerio): Evaluating a Volatile Organic Compound of Concern

ML Connell, CC Wu, JR Blount, A Haimbaugh… - International journal of …, 2023 - mdpi.com
Urban environments are afflicted by mixtures of anthropogenic volatile organic compounds
(VOCs). VOC sources that drive human exposure include vehicle exhaust, industrial …

Nontargeted metabolomic evidence for antagonism between tetracycline and its resistance bacteria underlying their obesogenic effects on Caenorhabditis elegans

Z Li, D Wu, Z Yu, C Cui, D Yin - Science of the Total Environment, 2023 - Elsevier
Environmental antibiotics raise serious health concerns due to their contribution to the
obesity prevalence. Moreover, antibiotics promote antibiotic-resistance bacteria (ARB) which …

N6-methyladenosine (M6A) in fetal offspring modifies mitochondrial gene expression following gestational nano-TiO2 inhalation exposure

A Kunovac, QA Hathaway, D Thapa, AJ Durr… - …, 2023 - Taylor & Francis
Abstract N6-methyladenosine (m6A) is the most prominent epitranscriptomic modification to
RNA in eukaryotes, but it's role in adaptive changes within the gestational environment are …

Prenatal benzene exposure in mice alters offspring hypothalamic development predisposing to metabolic disease in later life

L Koshko, S Scofield, L Debarba, L Stilgenbauer… - Chemosphere, 2023 - Elsevier
Maternal exposure to environmental contaminants during pregnancy poses a significant
threat to a developing fetus, as these substances can easily cross the placenta and disrupt …

Prenatal benzene exposure alters offspring hypothalamic development predisposing to metabolic disease in later life

L Koshko, S Scofield, L Debarba, L Stilgenbauer… - bioRxiv, 2023 - biorxiv.org
The hypothalamus is essential in the regulation of metabolism, notably during critical
windows of development. An abnormal hormonal and inflammatory milieu during …

RISING STARS: Sex differences in toxicant-associated fatty liver disease

B Wahlang - Journal of Endocrinology, 2023 - joe.bioscientifica.com
Based on biological sex, the consequential health outcomes from exposures to
environmental chemicals or toxicants can differ in disease pathophysiology, progression …