The evolving landscape of antibody–drug conjugates: In depth analysis of recent research progress

JM Sasso, R Tenchov, R Bird, KA Iyer… - Bioconjugate …, 2023 - ACS Publications
Antibody–drug conjugates (ADCs) are targeted immunoconjugate constructs that integrate
the potency of cytotoxic drugs with the selectivity of monoclonal antibodies, minimizing …

Therapeutic applications of nanobiotechnology

Y Dutt, RP Pandey, M Dutt, A Gupta, A Vibhuti… - Journal of …, 2023 - Springer
Nanobiotechnology, as a novel and more specialized branch of science, has provided a
number of nanostructures such as nanoparticles, by utilizing the methods, techniques, and …

Single cell analysis of PANoptosome cell death complexes through an expansion microscopy method

Y Wang, N Pandian, JH Han, B Sundaram… - Cellular and Molecular …, 2022 - Springer
In response to infection or sterile insults, inflammatory programmed cell death is an essential
component of the innate immune response to remove infected or damaged cells …

Phase II/III results of a trial of anti–tumor necrosis factor multivalent NANOBODY compound ozoralizumab in patients with rheumatoid arthritis

T Takeuchi, M Kawanishi, M Nakanishi… - Arthritis & …, 2022 - Wiley Online Library
Objective To assess the efficacy and safety of subcutaneous administration of 30 mg or 80
mg of ozoralizumab plus methotrexate (MTX) in patients with rheumatoid arthritis (RA) …

CDH17 nanobodies facilitate rapid imaging of gastric cancer and efficient delivery of immunotoxin

J Ma, X Xu, C Fu, P Xia, M Tian, L Zheng… - Biomaterials …, 2022 - spj.science.org
Background It is highly desirable to develop new therapeutic strategies for gastric cancer
given the low survival rate despite improvement in the past decades. Cadherin 17 (CDH17) …

Nanobody: a small antibody with big implications for tumor therapeutic strategy

S Sun, Z Ding, X Yang, X Zhao, M Zhao… - International Journal …, 2021 - Taylor & Francis
The development of monoclonal antibody treatments for successful tumor-targeted therapies
took several decades. However, the efficacy of antibody-based therapy is still confined and …

Anti-CTLA-4 nanobody as a promising approach in cancer immunotherapy

M Babamohamadi, N Mohammadi, E Faryadi… - Cell Death & …, 2024 - nature.com
Cancer is one of the most common diseases and causes of death worldwide. Since common
treatment approaches do not yield acceptable results in many patients, developing …

Efficacy and safety of the anti-TNF multivalent NANOBODY® compound ozoralizumab in patients with rheumatoid arthritis and an inadequate response to …

Y Tanaka, M Kawanishi, M Nakanishi… - Modern …, 2023 - academic.oup.com
Objective To assess the efficacy and safety through a 52-week treatment with subcutaneous
ozoralizumab at 30 or 80 mg in patients with active rheumatoid arthritis despite methotrexate …

Efficacy and safety of anti-TNF multivalent NANOBODY® compound 'ozoralizumab'without methotrexate co-administration in patients with active rheumatoid arthritis: a …

Y Tanaka, M Kawanishi, M Nakanishi… - Modern …, 2023 - academic.oup.com
Objectives The aim is to assess the efficacy and safety of a 52-week subcutaneous
ozoralizumab treatment at 30 and 80 mg without methotrexate (MTX) in active rheumatoid …

A nanobody‐on‐quantum dot displacement assay for rapid and sensitive quantification of the epidermal growth factor receptor (EGFR)

R Su, YT Wu, S Doulkeridou, X Qiu… - Angewandte Chemie …, 2022 - Wiley Online Library
Biosensing approaches that combine small, engineered antibodies (nanobodies) with
nanoparticles are often complicated. Here, we show that nanobodies with different C …