Natural products are mainly secondary metabolites produced by plants, microorganisms,
and animals, which are still abundant in modern drug discovery. Terpenoids are the most …

Terpenoids are a large class of plant-derived compounds, that constitute the main
components of essential oils and are widely used as natural flavors and fragrances. The …

Fermented peppers are usually obtained by the spontaneous fermentation of
microorganisms attached to fresh peppers, and the variable microbial composition would …

Background More than 2700 trace compounds were reported in Chinese Baijiu. Among
these compounds, odor-active compounds (OACs) can directly exhibit sensory …

Itaconic acid (IA) is a high-value organic acid with a plethora of industrial applications. In this
study, we seek to develop a microbial cell factory that could utilize waste cooking oil (WCO) …

Metabolic engineering of yeasts for terpenoid production has mostly focused on the
cytoplasm, whereas harnessing their organelles as subcellular factories has been …

L-methionine is an essential amino acid with versatile applications in food, feed, cosmetics
and pharmaceuticals. At present, the production of L-methionine mainly relies on chemical …

A synthetic microbial consortium for consolidated bioprocessing (CBP) is considered a
promising approach for the biochemical production owing to the efficient division of labor …

Pyrimidine nucleosides, as intermediate materials of significant commercial value, find
extensive applications in the pharmaceutical industry. However, the current production of …

Background Amyrin is an important triterpenoid and precursor to a wide range of cosmetic,
pharmaceutical and nutraceutical products. In this study, we metabolically engineered the …