Simple Summary Innate immune natural killer (NK) cells are capable of killing metastatic
cancer cells without activation by antigen-presenting cells beforehand. The cytotoxic effects …

Natural killer (NK) cells are lymphocytes of the innate immune system that monitor cell
surfaces of autologous cells for an aberrant expression of MHC class I molecules and cell …

Antibody-dependent cellular cytotoxicity (ADCC) is exerted by immune cells expressing
surface Fcγ receptors (FcγRs) against cells coated with antibody, such as virus-infected or …

Both the innate and adaptive immune systems contribute to tumor immunosurveillance in
mice and humans; however, there is a paucity of direct evidence of a role for natural killer …

In addition to malignant neoplastic cells, cancer tissues also include immune cells,
fibroblasts, and endothelial cells, including an abundant collection of growth factors …

Natural killer cells are powerful effectors of innate immunity that constitute a first line of
defense against cancer. NK cells express an array of germline-encoded receptors which …

The link between chronic immune activation and tumorigenesis is well established.
Compelling evidence has accumulated that histologic assessment of infiltration patterns of …

Lung cancer, the leading cause of cancer-related deaths worldwide, is a heterogeneous
disease comprising multiple histologic subtypes that harbor disparate mutational profiles …

Natural killer (NK) cells are central components of the innate immunity. In murine models, it
has been shown that NK cells can control both local tumor growth and metastasis due to …

Cancer is a dysregulated cellular level pathological condition that results in tumor formation
followed by metastasis. In the heterogeneous tumor architecture, cancer stem cells (CSCs) …