Brain-derived neurotrophic factor (BDNF) promotes neuroprotection and neuroregeneration.
In animal models of Parkinson's disease (PD), BDNF enhances the survival of dopaminergic …

Astrocytes, oligodendrocytes, and microglia are abundant cell types found in the central
nervous system and have been shown to play crucial roles in regulating both normal and …

Parkinson's disease (PD) is the second most common neurodegenerative disorder of the
elderly, presenting primarily with symptoms of motor impairment. The disease is diagnosed …

Parkinson's disease (PD) is one of the common progressive neurodegenerative disorders
with several motor and non-motor symptoms. Most of the motor symptoms may appear at a …

The present study demonstrates that blood samples can be used as a source of miRNA
identification associated to Parkinson's disease (PD). A set of six differentially expressed …

Furin is an important mammalian proprotein convertase that catalyzes the proteolytic
maturation of a variety of prohormones and proproteins in the secretory pathway. In the …

Brain-Derived Neurotrophic Factor (BDNF) is a dominant neurotrophic factor in the brain
which plays a crucial role in differentiation, regeneration and plasticity mechanisms. Binding …

Background Brain-derived neurotrophic factor (BDNF) is an abundant neurotrophin in the
adult brain. Serum BDNF levels might be used as a proxy for its central expression …

Brain-derived neurotrophic factor (BDNF) is the most widely distributed neurotrophin in the
CNS, where it plays several pivotal roles in synaptic plasticity and neuronal survival. As a …

Parkinson's disease is caused by a complex interplay of genetic and environmental factors.
Although a number of independent molecular pathways and processes have been …