[HTML][HTML] Phytochemicals in drug discovery—A confluence of tradition and innovation

P Chihomvu, A Ganesan, S Gibbons… - International Journal of …, 2024 - mdpi.com
Phytochemicals have a long and successful history in drug discovery. With recent
advancements in analytical techniques and methodologies, discovering bioactive leads from …

Microbial metabolites: the emerging hotspot of antiviral compounds as potential candidates to avert viral pandemic alike COVID-19

T Raihan, MF Rabbee, P Roy, S Choudhury… - Frontiers in molecular …, 2021 - frontiersin.org
The present global COVID-19 pandemic caused by the noble pleomorphic severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has created a vulnerable situation in the …

[PDF][PDF] Beta Elemene induces cytotoxic effects in FLT3 ITD-mutated acute myeloid leukemia by modulating apoptosis.

A Alafnan, R Dogan, O Bender, I Celik… - European Review for …, 2023 - researchgate.net
Beta Elemene induces cytotoxic effects in FLT3 ITD-mutated acute myeloid leukemia by
modulating apoptosis Page 1 3270 Abstract. – OBJECTIVE: β-Elemene, a sesquiterpene with a …

In-silico investigation of E8 surface protein of the monkeypox virus to identify potential therapeutic agents

S Podduturi, D Vemula, S Singothu… - Journal of Biomolecular …, 2024 - Taylor & Francis
The re-emergence of the monkeypox virus (MPXV) in 2022 has become a global issue. The
virus was first found in Denmark in 1958. The first human MPXV disease was reported in …

Allosteric Modulation of the Main Protease (MPro) of SARS-CoV-2 by Casticin—Insights from Molecular Dynamics Simulations

JO Mensah, GB Ampomah, EN Gasu, AK Adomako… - Chemistry Africa, 2022 - Springer
Inhibition of the main protease (Mpro) of SARS-CoV-2 has been suggested to be vital in
shutting down viral replication in a host. Most efforts aimed at inhibiting MPro activity have …

Comparative Analysis of the Efficiency of Medicinal Plants for the Treatment and Prevention of COVID‐19

V Kamkin, A Kamarova, B Shalabayev… - International Journal …, 2022 - Wiley Online Library
The COVID‐19 pandemic has once again prompted people to resort to the remedies of folk
and alternative medicine. Medicinal plants, because of their chemical composition …

The efficacy of traditional medicinal plants in modulating the main protease of SARS‐CoV‐2 and cytokine storm

J Choe, P Har Yong, Z Xiang Ng - Chemistry & Biodiversity, 2022 - Wiley Online Library
Selected traditional medicinal plants exhibit therapeutic effects in coronavirus disease
(Covid‐19) patients. This review aims to identify the phytochemicals from five traditional …

Bioprospecting phytochemicals of Rosmarinus officinalis L. for targeting SARS-CoV-2 main protease (Mpro): a computational study

U Patel, K Desai, RC Dabhi, JJ Maru… - Journal of Molecular …, 2023 - Springer
Context The persistent spread of highly contagious COVID-19 disease is one of the
deadliest occurrences in the history of mankind. Despite the distribution of numerous …

Insights of phytoremediation mechanisms for viruses based on in-vitro, in-vivo and in-silico assessments of selected herbal plants

D Zure, HWD Kuo, A Drizo - Chemosphere, 2024 - Elsevier
Waterborne pathogenic viruses present unrelenting challenges to the global health and
wastewater treatment industry. Phytoremediation offers promising solutions for wastewater …

Applications of some advanced sequencing, analytical, and computational approaches in medicinal plant research: a review

D Singh, N Mittal, S Verma, A Singh… - Molecular Biology …, 2024 - Springer
The potential active chemicals found in medicinal plants, which have long been employed
as natural medicines, are abundant. Exploring the genes responsible for producing these …