The Rise of Boron-Containing Compounds: Advancements in Synthesis, Medicinal Chemistry, and Emerging Pharmacology

RJ Grams, WL Santos, IR Scorei, A Abad-García… - Chemical …, 2024 - ACS Publications
Boron-containing compounds (BCC) have emerged as important pharmacophores. To date,
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …

New insights into boron essentiality in humans and animals

A Biţă, IR Scorei, TA Bălşeanu, MV Ciocîlteu… - International Journal of …, 2022 - mdpi.com
Boron (B) is considered a prebiotic chemical element with a role in both the origin and
evolution of life, as well as an essential micronutrient for some bacteria, plants, fungi, and …

Nicotinamide Riboside, a Promising Vitamin B3 Derivative for Healthy Aging and Longevity: Current Research and Perspectives

A Biţă, IR Scorei, MV Ciocîlteu, OE Nicolaescu… - Molecules, 2023 - mdpi.com
Many studies have suggested that the oxidized form of nicotinamide adenine dinucleotide
(NAD+) is involved in an extensive spectrum of human pathologies, including …

Effects of boron-containing compounds on liposoluble hormone functions

E Estevez-Fregoso, A Kilic, D Rodríguez-Vera… - Inorganics, 2023 - mdpi.com
Boron-containing compounds (BCC), particularly boronic acids and derivatives, are being
increasingly tested as diagnostic and therapeutic agents. Some effects of BCC involve …

[HTML][HTML] Selected physiological effects of boron compounds for animals and humans. A review

M Białek, M Czauderna, KA Krajewska… - Journal of Animal and …, 2019 - jafs.com.pl
Boron is a metalloid that plays an important role in the functioning of cell membrane,
enzymatic reactions and the hormonal and mineral metabolism of animals. Boron is also …

[HTML][HTML] Pivotal role of boron supplementation on bone health: A narrative review

M Rondanelli, MA Faliva, G Peroni, V Infantino… - Journal of Trace …, 2020 - Elsevier
Background Boron is a trace element that plays an important role in numerous biological
functions, including calcium metabolism, growth and maintenance of bone tissue. However …

[HTML][HTML] Boron-containing compounds in Dentistry: A narrative review

I Mitruţ, IR Scorei, HO Manolea, A Biţă… - Romanian Journal of …, 2022 - ncbi.nlm.nih.gov
Research on the use of boron (B) in the field of oral health has gained momentum in recent
years, with various studies on the possibilities of using various B-containing compounds …

Boric acid-functionalized silver nanoparticles as SERS substrate for sensitive and rapid detection of fructose in artificial urine

J Shen, G Chen, Z Yang, Y Wu, C Ma, L Li… - … Acta Part A: Molecular …, 2023 - Elsevier
The accurate detection of fructose in human urine can help prevent and screen for diseases
such as fructokinase deficiency and hereditary fructose intolerance. Surface-enhanced …

Boron-containing compounds for prevention, diagnosis, and treatment of human metabolic disorders

CC Ri, CR Mf, S IR, SU MA - Biological trace element research, 2023 - Springer
The application of natural and synthetic boron-containing compounds (BCC) in biomedical
field is expanding. BCC have effects in the metabolism of living organisms. Some boron …

Natural flavonols as probes for direct determination of borax: From conventional fluorescence analysis to paper-based smartphone sensing

J Xia, J Huang, H Zhang, N Zhang, F Li, P Zhou, L Zhou… - Talanta, 2024 - Elsevier
Borax is strictly regulated in the food processing and pharmaceutical industry due to its
physiological toxicity, and the development of a direct analytical method is essential for …