Applications of single-cell RNA sequencing in atopic dermatitis and psoriasis

D Xia, Y Wang, Y Xiao, W Li - Frontiers in immunology, 2022 - frontiersin.org
Single-cell RNA sequencing (scRNA-seq) is a novel technology that characterizes
molecular heterogeneity at the single-cell level. With the development of more automated …

Pellino-1 promotes intrinsic activation of skin-resident IL-17A–producing T cells in psoriasis

SH Kim, J Oh, WS Roh, J Park, KB Chung… - Journal of Allergy and …, 2023 - Elsevier
Background Psoriasis is a chronically relapsing inflammatory skin disease primarily
perpetuated by skin-resident IL-17–producing T (T17) cells. Pellino-1 (Peli1) belongs to a …

Skin in the game: a review of single-cell and spatial transcriptomics in dermatological research

S Schepps, J Xu, H Yang, J Mandel, J Mehta… - Clinical Chemistry and …, 2024 - degruyter.com
Single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics (ST) are two emerging
research technologies that uniquely characterize gene expression microenvironments on a …

Identification of diagnostic molecules and potential therapeutic agents for atopic dermatitis by single-cell RNA sequencing combined with a systematic computing …

X Zhang, C Ding, Z Zhao - Functional & Integrative Genomics, 2023 - Springer
Atopic dermatitis (AD) is composed of highly flexible cellular participants. To better
understand its pathobiology and molecular regulation mechanisms, it is necessary to …

Single-cell RNA-seq and bulk-seq identify RAB17 as a potential regulator of angiogenesis by human dermal microvascular endothelial cells in diabetic foot ulcers

H Du, S Li, J Lu, L Tang, X Jiang, X He, J Liang… - Burns & …, 2023 - academic.oup.com
Background Angiogenesis is crucial in diabetic wound healing and is often impaired in
diabetic foot ulcers (DFUs). Human dermal microvascular endothelial cells (HDMECs) are …

Laser-Capture Microdissection-Based RNA Sequencing for Profiling Mouse and Human Sebaceous Gland Transcriptomes

JC Harris, SM Prouty, MA Nelson… - The Journal of …, 2024 - pubmed.ncbi.nlm.nih.gov
Laser-Capture Microdissection-Based RNA Sequencing for Profiling Mouse and Human
Sebaceous Gland Transcriptomes Laser-Capture Microdissection-Based RNA Sequencing for …