Lectins are a unique group of nonimmune carbohydrate-binding proteins or glycoproteins
that exhibit specific and reversible carbohydrate-binding activity in a non-catalytic manner …

Due to their remarkable structural diversity, glycans play important roles as recognition
molecules on cell surfaces of living organisms. Carbohydrates exist in numerous isomeric …

Pneumolysin (PLY), a major virulence factor of Streptococcus pneumoniae, perforates
cholesterol-rich lipid membranes. PLY protomers oligomerize as rings on the membrane …

Secretory pore-forming proteins (PFPs) have been identified in organisms from all kingdoms
of life. Our studies with the toad species Bombina maxima found an interaction network …

The invertebrate cytolysin lysenin is a member of the aerolysin family of pore-forming toxins
that includes many representatives from pathogenic bacteria. Here we report the crystal …

Since the first record of the five founder members of the group of Natterin proteins in the
venom of the medically significant fish Thalassophryne nattereri, new sequences have been …

Aerolysin is the founding member of a major class of β-pore-forming toxins (β-PFTs) found
throughout all kingdoms of life. PFTs are cytotoxic proteins produced as soluble monomers …

Aeromonas species are opportunistic bacteria causing a vast spectrum of human diseases,
including skin and soft tissue infections, meningitis, endocarditis, peritonitis, gastroenteritis …

Aerolysin-like pore-forming proteins are an important family of proteins able to efficiently
damage membranes of target cells by forming transmembrane pores. They are …

Mucosal surfaces are of key importance in protecting animals against external threats
including pathogens. In the mucosal surfaces, host molecules interact with non-self to …