Long non-coding RNA (lncRNA) H19 in human cancer: From proliferation and metastasis to therapy

M Hashemi, MS Moosavi, HM Abed, M Dehghani… - Pharmacological …, 2022 - Elsevier
Initiation and development of cancer depend on multiple factors that mutations in genes and
epigenetic level can be considered as important drivers. Epigenetic factors include a large …

Long non-coding RNA mediated drug resistance in breast cancer

D Singh, YG Assaraf, RN Gacche - Drug Resistance Updates, 2022 - Elsevier
Breast cancer is one of the most prevalent cancers in women and a leading cause of
mortality. As per the GLOBCAN report of 2021, breast cancer has surpassed lung cancer …

[HTML][HTML] EMT mechanism in breast cancer metastasis and drug resistance: Revisiting molecular interactions and biological functions

M Hashemi, HZ Arani, S Orouei, S Fallah… - Biomedicine & …, 2022 - Elsevier
One of the malignant tumors in women that has involved both developed and developing
countries is breast cancer. Similar to other types of tumors, breast cancer cells demonstrate …

[HTML][HTML] Exosome-mediated lncRNA AFAP1-AS1 promotes trastuzumab resistance through binding with AUF1 and activating ERBB2 translation

M Han, Y Gu, P Lu, J Li, H Cao, X Li, X Qian, C Yu… - Molecular cancer, 2020 - Springer
Background Although trastuzumab provides significant clinical benefit for HER2-positive
breast cancers, responses are limited by the emergence of resistance. Recent evidence …

[HTML][HTML] Deciphering the tRNA-derived small RNAs: origin, development, and future

B Liu, J Cao, X Wang, C Guo, Y Liu, T Wang - Cell Death & Disease, 2021 - nature.com
Transfer RNA (tRNA)-derived small RNAs (tsRNAs), a novel category of small noncoding
RNAs, are enzymatically cleaved from tRNAs. Previous reports have shed some light on the …

The role of non‐coding RNAs in drug resistance of oral squamous cell carcinoma and therapeutic potential

X Meng, QY Lou, WY Yang, YR Wang… - Cancer …, 2021 - Wiley Online Library
Oral squamous cell carcinoma (OSCC), the eighth most prevalent cancer in the world, arises
from the interaction of multiple factors including tobacco, alcohol consumption, and betel …

[HTML][HTML] RETRACTED ARTICLE: exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer

M Han, J Hu, P Lu, H Cao, C Yu, X Li, X Qian… - Cell death & …, 2020 - nature.com
Trastuzumab is commonly used in the treatment of human epidermal growth factor receptor-
2 positive (HER-2+) breast cancer, but its efficacy is often limited by the emergence of …

Chitosan‐gelatin‐EGCG nanoparticle‐meditated LncRNA TMEM44‐AS1 silencing to activate the P53 signaling pathway for the synergistic reversal of 5‐FU resistance …

M Zhou, J Dong, J Huang, W Ye, Z Zheng… - Advanced …, 2022 - Wiley Online Library
Chemoresistance is one of the leading causes of therapeutic failure in gastric cancer (GC)
treatment. Recent studies have shown lncRNAs play pivotal roles in regulating GC …

[HTML][HTML] lncRNA and breast cancer: Progress from identifying mechanisms to challenges and opportunities of clinical treatment

H Jin, W Du, W Huang, J Yan, Q Tang, Y Chen… - … Therapy-Nucleic Acids, 2021 - cell.com
Breast cancer is a malignant tumor that has a high mortality rate and mostly occurs in
women. Although significant progress has been made in the implementation of personalized …

[HTML][HTML] Insights into biological role of LncRNAs in epithelial-mesenchymal transition

JT Cheng, L Wang, H Wang, FR Tang, WQ Cai, G Sethi… - Cells, 2019 - mdpi.com
Long non-coding RNAs (lncRNAs) are versatile regulators of gene expression and play
crucial roles in diverse biological processes. Epithelial-mesenchymal transition (EMT) is a …