Fibrinogen conversion into insoluble fibrin and the formation of a stable clot is the final step
of the coagulation cascade. Fibrin clot porosity and its susceptibility to plasmin-mediated …

Fibrin is a major component of thrombi formed on the surface of atherosclerotic plaques.
Fibrin accumulation as a consequence of local blood coagulation activation takes place …

Background: Large-scale human and mechanistic mouse studies indicate a strong
relationship between the microbiome-dependent metabolite trimethylamine N-oxide (TMAO) …

Neutrophils represent up to 70% of circulating leukocytes in healthy humans and combat
infection mostly by phagocytosis, degranulation and NETosis. It has been reported that …

Background: Abdominal aortic aneurysm represents a distinct group of vascular lesions, in
terms of surveillance and treatment. Screening and follow-up of patients via duplex …

BACKGROUND: Platelets play an important role in cardiovascular and cerebrovascular
diseases. Abdominal aortic aneurysm (AAA) is a highly lethal, atherosclerosis-related …

Aims Abdominal aortic aneurysm (AAA) is a highly lethal disease with progressive dilatation
of the abdominal aorta accompanied by degradation and remodelling of the vessel wall due …

Background: People with HIV (PWH) have an increased risk of cardiovascular disease.
Previous cross-sectional data suggest there is a higher prevalence of abdominal aortic …

Background Aortic disease (aortic aneurysm (AA), dissection (AD)) is a serious threat to
patient lives. Little is currently known about the molecular mechanisms and immune …

Background Abdominal aortic aneurysm (AAA) is a complicated aortic dilatation disease.
Metabolomics is an emerging system biology method. This aim of this study was to identify …