[HTML][HTML] Acute Myeloid Leukemia in Older Patients: From New Biological Insights to Targeted Therapies
P Niscola, V Gianfelici, G Catalano… - Current …, 2024 - pmc.ncbi.nlm.nih.gov
Acute myeloid leukemia (AML) is a heterogeneous blood-related neoplasm that
predominantly afflicts older adults with a poor prognosis due to their physical condition and …
predominantly afflicts older adults with a poor prognosis due to their physical condition and …
[HTML][HTML] PX-478 induces apoptosis in acute myeloid leukemia under hypoxia by inhibiting the PI3K/AKT/mTOR pathway through downregulation of GBE1
W Liu, C Dou, C Zhang, P Chen, S Zhang… - Biochemical …, 2024 - Elsevier
Acute myeloid leukemia (AML) is a highly heterogeneous hematologic malignancy
characterized by limited therapeutic options and a pronounced tendency for relapse. PX …
characterized by limited therapeutic options and a pronounced tendency for relapse. PX …
Menin Inhibitors: New Targeted Therapies for Specific Genetic Subtypes of Difficult-to-Treat Acute Leukemias
P Niscola, V Gianfelici, M Giovannini, D Piccioni… - Cancers, 2025 - mdpi.com
Menin (MEN1) is a well-recognized powerful tumor promoter in acute leukemias (AL) with
KMT2A rearrangements (KMT2Ar, also known as MLL) and mutant nucleophosmin 1 …
KMT2A rearrangements (KMT2Ar, also known as MLL) and mutant nucleophosmin 1 …
[PDF][PDF] Latest Insights and Progress in the Clinical Management of Elderly Patients with Acute Myeloid Leukemia: From Genetic Advancements to Targeted Treatments
P NISCOLA, NI Noguera, V Gianfelici, L Cesini… - 2024 - preprints.org
Acute myeloid leukemias (AMLs) are heterogeneous hematologic cancers that occur
prevalently in older patients as the result of a complex pathobiology. The clinical outcomes …
prevalently in older patients as the result of a complex pathobiology. The clinical outcomes …