Gabapentinoid pharmacology in the context of emerging misuse liability

KE Evoy, AM Peckham, JR Covvey… - The Journal of …, 2021 - Wiley Online Library
This article will review the epidemiology and pharmacology of gabapentinoids (gabapentin
and pregabalin) relevant to their emerging misuse potential and provide guidance for …

A comprehensive investigation of interactions between antipsychotic drug quetiapine and human serum albumin using multi-spectroscopic, biochemical, and …

S Zargar, TA Wani, NA Alsaif, AIA Khayyat - Molecules, 2022 - mdpi.com
Quetiapine (QTP) is a short-acting atypical antipsychotic drug that treats schizophrenia or
manic episodes of bipolar disorder. Human serum albumin (HSA) is an essential transport …

Safety of antipsychotic drugs: a systematic review of disproportionality analysis studies

D Cepaityte, S Siafis, G Papazisis - Behavioural Brain Research, 2021 - Elsevier
Antipsychotic drugs are commonly prescribed, mainly for the treatment of schizophrenia and
other psychotic disorders. Disproportionality analysis of pharmacovigilance data from …

Comparing acute kidney injury reports among antibiotics: a pharmacovigilance study of the FDA adverse event reporting system (FAERS)

TM Patek, C Teng, KE Kennedy, CA Alvarez, CR Frei - Drug Safety, 2020 - Springer
Background A study using the US FDA Adverse Event Reporting System (FAERS) found
significant acute kidney injury (AKI) reporting associations with vancomycin …

Misuse of prescription and over-the-counter drugs to obtain illicit highs: How pharmacists can prevent abuse

S Chiappini, A Guirguis, J Corkery… - The Pharmaceutical …, 2020 - uhra.herts.ac.uk
There have been increasing reports of misuse of a range of prescription and over-the-
counter (OTC) drugs for recreational purposes. The use of psychoactive pharmaceuticals …

Combined effects of quetiapine and opioids: A study of autopsy cases, drug users and sedation in rats

FD Andersen, S Joca, V Hvingelby, S Arjmand… - Addiction …, 2022 - Wiley Online Library
Fatal opioid poisonings often involve methadone or morphine. This study aimed to elucidate
if quetiapine, a widely used sedative antipsychotic medication, may increase the risk of fatal …

Hypoglycemia associated with antibiotics alone and in combination with sulfonylureas and meglitinides: an epidemiologic surveillance study of the FDA Adverse …

KE Kennedy, C Teng, TM Patek, CR Frei - Drug safety, 2020 - Springer
Introduction Fluoroquinolones, clarithromycin, linezolid, tigecycline, cefditoren, doxycycline,
and trimethoprim–sulfamethoxazole are known to be associated with hypoglycemia, but few …

[HTML][HTML] Rhabdomyolysis associations with antibiotics: a pharmacovigilance study of the FDA Adverse Event Reporting System (FAERS)

C Teng, C Baus, JP Wilson, CR Frei - International Journal of …, 2019 - ncbi.nlm.nih.gov
Abstract Introduction: Daptomycin, macrolides, trimethoprim-sulfamethoxazole, linezolid,
fluoroquinolones, and cefdinir are known to be associated with rhabdomyolysis. Other …

Cardiac adverse events associated with quetiapine: disproportionality analysis of FDA adverse event reporting system

Y Shu, Y Ding, L Liu, Q Zhang - CNS Neuroscience & …, 2023 - Wiley Online Library
Objective Quetiapine, an atypical second‐generation antipsychotic drug, is approved for
treatment of schizophrenia, bipolar disorder, and depression. Due to the limitations of …

Focus on clozapine withdrawal-and misuse-related cases as reported to the European Medicines Agency (EMA) pharmacovigilance database

S Chiappini, F Schifano, JM Corkery, A Guirguis - Brain sciences, 2020 - mdpi.com
Background: Clozapine is of high clinical relevance for the management of both treatment-
resistant schizophrenia and psychotic disturbances with concurrent drug misuse. Although …