The neurobiology of brain and cognitive reserve: mental and physical activity as modulators of brain disorders
J Nithianantharajah, AJ Hannan - Progress in neurobiology, 2009 - Elsevier
The concept of 'cognitive reserve', and a broader theory of 'brain reserve', were originally
proposed to help explain epidemiological data indicating that individuals who engaged in …
proposed to help explain epidemiological data indicating that individuals who engaged in …
Learned helplessness: unique features and translational value of a cognitive depression model
B Vollmayr, P Gass - Cell and tissue research, 2013 - Springer
The concept of learned helplessness defines an escape or avoidance deficit after
uncontrollable stress and is regarded as a depression-like coping deficit in aversive but …
uncontrollable stress and is regarded as a depression-like coping deficit in aversive but …
Infusing neuroscience into teacher professional development
Bruer advocated connecting neuroscience and education indirectly through the intermediate
discipline of psychology. We argue for a parallel route: The neurobiology of learning, and in …
discipline of psychology. We argue for a parallel route: The neurobiology of learning, and in …
Prevention and treatment of drug addiction by environmental enrichment
Environmental enrichment (EE) has been shown to have powerful beneficial effects on a
variety of physiological and pathological processes. Accumulating evidence indicates that …
variety of physiological and pathological processes. Accumulating evidence indicates that …
Improving reproducibility in animal research by splitting the study population into several 'mini-experiments'
In light of the hotly discussed 'reproducibility crisis', a rethinking of current methodologies
appears essential. Implementing multi-laboratory designs has been shown to enhance the …
appears essential. Implementing multi-laboratory designs has been shown to enhance the …
Activity-dependent, stress-responsive BDNF signaling and the quest for optimal brain health and resilience throughout the lifespan
SM Rothman, MP Mattson - Neuroscience, 2013 - Elsevier
During development of the nervous system, the formation of connections (synapses)
between neurons is dependent upon electrical activity in those neurons, and neurotrophic …
between neurons is dependent upon electrical activity in those neurons, and neurotrophic …
Short‐term environmental enrichment, in the absence of exercise, improves memory, and increases NGF concentration, early neuronal survival, and synaptogenesis …
AM Birch, NB McGarry, ÁM Kelly - Hippocampus, 2013 - Wiley Online Library
Environmental manipulations can enhance neuroplasticity in the brain, with enrichment‐
induced cognitive improvements being linked to increased expression of growth factors …
induced cognitive improvements being linked to increased expression of growth factors …
The double edged sword of neural plasticity: increasing serotonin levels leads to both greater vulnerability to depression and improved capacity to recover
I Branchi - Psychoneuroendocrinology, 2011 - Elsevier
Major depression is a chronic, recurring and potentially life-threatening illness that affects up
to 10% of the population worldwide. Pharmacological and genetic studies highlight the …
to 10% of the population worldwide. Pharmacological and genetic studies highlight the …
Altered serotonin receptor expression is associated with depression-related behavior in the R6/1 transgenic mouse model of Huntington's disease
Dysregulation of the serotonergic signaling system has been implicated in the pathology of
mood disorders including depression, and various rodent models of disrupted serotonergic …
mood disorders including depression, and various rodent models of disrupted serotonergic …
Paternal social enrichment effects on maternal behavior and offspring growth
R Mashoodh, B Franks, JP Curley… - Proceedings of the …, 2012 - National Acad Sciences
Paternal environmental experiences are significant predictors of developmental outcomes in
offspring and can occur even in the absence of paternal care. Although there has been a …
offspring and can occur even in the absence of paternal care. Although there has been a …