[HTML][HTML] Mitochondrial complex II and V activity is enhanced in pediatric acute myeloid leukemia

S Chaudhary, S Ganguly, A Singh… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Background: Mitochondrial bioenergetic alterations are commonly observed metabolic
adaptation in malignancies including acute myeloid leukemia (AML). Mitochondrial DNA …

Molecular evaluation of gene mutation profiles and copy number variations in pediatric acute myeloid leukemia

JP Meena, N Pathak, AK Gupta, S Bakhshi, R Gupta… - Leukemia Research, 2022 - Elsevier
Background The objectives of this study were to investigate the mutation profiles of targeted
genes and copy number variations (CNVs) in normal cytogenetics (CN) pediatric acute …

Allogeneic hematopoietic stem cell transplant in pediatric acute myeloid leukemia: Lessons learnt from a tertiary care center in India

S Arora, D Pushpam, A Tiwari… - Pediatric …, 2021 - Wiley Online Library
There is paucity of data on outcomes of MSD‐HSCT in children with relapsed or high‐risk
AML from developing countries, which have unique challenges including adverse host …

[HTML][HTML] Frequency and pattern of chromosomal abnormalities in acute myeloid leukemia from Western India: A retrospective study

BR Vundinti, S Korgaonkar, S Dhangar… - Journal of Cancer …, 2023 - journals.lww.com
Aims: The aim of the present study was to study the pattern and frequency of chromosomal
aberrations in acute myeloid leukemia (AML) subgroups from western India. Settings and …

[HTML][HTML] A comprehensive analysis of cytogenetics, molecular profile, and survival among pediatric acute myeloid leukemia: a prospective study from a tertiary referral …

JP Meena, H Makkar, AK Gupta, S Bakhshi… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Background and aims: The objectives of this study were to investigate the cyto-molecular
profile and survival of pediatric acute myeloid leukemia (AML). Methods: This prospective …

[HTML][HTML] Pediatric acute myeloid leukemia with breast chloromas

MS Gallardo, R Joyrich, JW Taub - EJHaem, 2023 - ncbi.nlm.nih.gov
FIGURE 1(A) Several nodular masses demonstrated in both breasts with
fluorodeoxyglucose (FDG) uptake (standardized uptake value [SUV] max: 2.9 on right breast …

Decoding mitochondrial genes in pediatric AML and development of a novel prognostic mitochondrial gene signature

S Chaudhary, S Ganguly, JK Palanichamy, A Singh… - medRxiv, 2022 - medrxiv.org
Background Gene expression profile of mitochondrial-related genes is not well deciphered
in pediatric acute myeloid leukaemia (AML). We aimed to identify mitochondria-related …

Molecular genetic characterization of acute myeloid leukemia with isolated trisomy of chromosomes 4, 11, and 21

F Zhou, H Shen, Z Wang, H Hua, P Wu… - International Journal …, 2022 - Wiley Online Library
Background Autosomal trisomy is a relatively rare abnormality observed in AML, occurring
singly or as a secondary event in association with other karyotypic changes, and associated …

Croton caudatus Geiseler Induces Differentiation of the Acute Myeloid Leukemia cell lines

TC Machathoibi, LS Singh - bioRxiv, 2022 - biorxiv.org
Croton caudatus Geiseler (CCG) is a traditional medicinal plant and it has also been
reported as having anticancer activity. However, most of the studies of the anticancer activity …

[PDF][PDF] Genetics of Acute Myeloid Leukemia—A Paradigm Shift

N Rastogi - Indian Pediatr, 2018 - indianpediatrics.net
It was the spring of 1972 when Janet Rowley noticed that a patient with acute myeloid
leukemia (AML) had abnormalities in his chromosomes. She went on to publish her findings …