Alcohol dehydrogenases as catalysts in organic synthesis
Alcohol dehydrogenases (ADHs) have become important catalysts for stereoselective
oxidation and reduction reactions of alcohols, aldehydes and ketones. The aim of this …
oxidation and reduction reactions of alcohols, aldehydes and ketones. The aim of this …
Enzymatic strategies for asymmetric synthesis
M Hall - RSC Chemical Biology, 2021 - pubs.rsc.org
Enzymes, at the turn of the 21st century, are gaining a momentum. Especially in the field of
synthetic organic chemistry, a broad variety of biocatalysts are being applied in an …
synthetic organic chemistry, a broad variety of biocatalysts are being applied in an …
Accessing non-natural reactivity by irradiating nicotinamide-dependent enzymes with light
Enzymes are ideal for use in asymmetric catalysis by the chemical industry, because their
chemical compositions can be tailored to a specific substrate and selectivity pattern while …
chemical compositions can be tailored to a specific substrate and selectivity pattern while …
Artificial Multienzyme Scaffolds: Pursuing in Vitro Substrate Channeling with an Overview of Current Progress
Artificial multienzyme scaffolds are being developed for in vitro cascaded biocatalytic activity
and, in particular, accessing substrate channeling. This review covers progress in this field …
and, in particular, accessing substrate channeling. This review covers progress in this field …
Direct alkylation of amines with primary and secondary alcohols through biocatalytic hydrogen borrowing
SL Montgomery, J Mangas‐Sanchez… - Angewandte …, 2017 - Wiley Online Library
The reductive aminase from Aspergillus oryzae (AspRedAm) was combined with a single
alcohol dehydrogenase (either metagenomic ADH‐150, an ADH from Sphingobium …
alcohol dehydrogenase (either metagenomic ADH‐150, an ADH from Sphingobium …
One-Pot Sequential Two-Step Photo-Biocatalytic Deracemization of sec-Alcohols Combining Photocatalytic Oxidation and Bioreduction
A Rudzka, N Antos, T Reiter, W Kroutil… - ACS …, 2024 - ACS Publications
Chiral alcohols are versatile building blocks and are of particular interest in the asymmetric
synthesis of nonracemic active pharmaceutical ingredients, agrochemicals, fragrances …
synthesis of nonracemic active pharmaceutical ingredients, agrochemicals, fragrances …
[HTML][HTML] Efficient reductive desymmetrization of bulky 1, 3-cyclodiketones enabled by structure-guided directed evolution of a carbonyl reductase
X Chen, H Zhang, MA Maria-Solano, W Liu, J Li… - Nature Catalysis, 2019 - nature.com
Abstract Reductive desymmetrization of 2, 2-disubstituted prochiral 1, 3-cyclodiketones to 2,
2-disubstituted-3-hydroxycycloketones is a highly desired transformation for the construction …
2-disubstituted-3-hydroxycycloketones is a highly desired transformation for the construction …
[HTML][HTML] Impact and relevance of alcohol dehydrogenase enantioselectivities on biotechnological applications
AA Koesoema, DM Standley, T Senda… - Applied microbiology and …, 2020 - Springer
Alcohol dehydrogenases (ADHs) catalyze the reversible reduction of a carbonyl group to its
corresponding alcohol. ADHs are widely employed for organic synthesis due to their lack of …
corresponding alcohol. ADHs are widely employed for organic synthesis due to their lack of …
The Synthesis of Chiral γ‐Lactones by Merging Decatungstate Photocatalysis with Biocatalysis
The implementation of light‐driven catalytic processes in biocatalysis opens a golden
window of opportunities. We hereby report the merging of photocatalytic C− C bond …
window of opportunities. We hereby report the merging of photocatalytic C− C bond …
[HTML][HTML] Fungal indole alkaloid biogenesis through evolution of a bifunctional reductase/Diels–Alderase
Prenylated indole alkaloids such as the calmodulin-inhibitory malbrancheamides and
anthelmintic paraherquamides possess great structural diversity and pharmaceutical utility …
anthelmintic paraherquamides possess great structural diversity and pharmaceutical utility …