Gene–environment interactions in Alzheimer disease: the emerging role of epigenetics
L Migliore, F Coppedè - Nature Reviews Neurology, 2022 - nature.com
With the exception of a few monogenic forms, Alzheimer disease (AD) has a complex
aetiology that is likely to involve multiple susceptibility genes and environmental factors. The …
aetiology that is likely to involve multiple susceptibility genes and environmental factors. The …
[HTML][HTML] Integrative multi-omics and systems bioinformatics in translational neuroscience: A data mining perspective
Bioinformatic analysis of large and complex omics datasets has become increasingly useful
in modern day biology by providing a great depth of information, with its application to …
in modern day biology by providing a great depth of information, with its application to …
Toxicity analysis of endocrine disrupting pesticides on non-target organisms: A critical analysis on toxicity mechanisms
V Kumar, N Sharma, P Sharma, R Pasrija… - Toxicology and Applied …, 2023 - Elsevier
Endocrine disrupting compounds are the chemicals which mimics the natural endocrine
hormones and bind to the receptors made for the hormones. Upon binding they activate the …
hormones and bind to the receptors made for the hormones. Upon binding they activate the …
Pesticides at brain borders: Impact on the blood-brain barrier, neuroinflammation, and neurological risk trajectories
N Cresto, I Forner-Piquer, A Baig, M Chatterjee… - Chemosphere, 2023 - Elsevier
Pesticides are omnipresent, and they pose significant environmental and health risks.
Translational studies indicate that acute exposure to high pesticide levels is detrimental, and …
Translational studies indicate that acute exposure to high pesticide levels is detrimental, and …
Effect of perinatal exposure to glyphosate and its mixture with 2, 4-D and dicamba on rat dam kidney and thyroid function and offspring's health
The increasing use of the herbicide mixture of glyphosate, dicamba and 2-4-D to deal with
glyphosate-resistant weeds raises concerns regarding human health and environmental …
glyphosate-resistant weeds raises concerns regarding human health and environmental …
Gene× environment interactions in autism spectrum disorders
K Keil-Stietz, PJ Lein - Current topics in developmental biology, 2023 - Elsevier
There is credible evidence that environmental factors influence individual risk and/or
severity of autism spectrum disorders (hereafter referred to as autism). While it is likely that …
severity of autism spectrum disorders (hereafter referred to as autism). While it is likely that …
Role of the Exposome in Neurodegenerative Disease: Recent Insights and Future Directions
SA Sakowski, EJ Koubek, KS Chen… - Annals of …, 2024 - Wiley Online Library
Neurodegenerative diseases are increasing in prevalence and place a significant burden on
society. The causes are multifactorial and complex, and increasing evidence suggests a …
society. The causes are multifactorial and complex, and increasing evidence suggests a …
Neurotoxicity of Pyrethroids in exacerbating neurodegenerative diseases: From animals' models to humans' studies
R Arsuffi-Marcon, LG Souza, A Santos-Miranda… - Chemico-Biological …, 2024 - Elsevier
Neurodegenerative diseases are associated with diverse symptoms, both motor and mental.
Genetic and environmental factors can trigger neurodegenerative diseases. Chemicals as …
Genetic and environmental factors can trigger neurodegenerative diseases. Chemicals as …
Ancestors' Gift: Parental Early Exposure to the Environmentally Realistic Pesticide Mixture Drives Offspring Phenotype in a Larger Extent Than Direct Exposure in the …
T Sol Dourdin, K Guyomard, M Rabiller… - Environmental …, 2024 - ACS Publications
Marine organisms are threatened by the presence of pesticides in coastal waters. Among
them, the Pacific oyster is one of the most studied invertebrates in marine ecotoxicology …
them, the Pacific oyster is one of the most studied invertebrates in marine ecotoxicology …
Epigenome modulation induced by ketogenic diets
P Ungaro, IC Nettore, F Franchini, G Palatucci… - Nutrients, 2022 - mdpi.com
Ketogenic diets (KD) are dietary strategies low in carbohydrates, normal in protein, and high,
normal, or reduced in fat with or without (Very Low-Calories Ketogenic Diet, VLCKD) a …
normal, or reduced in fat with or without (Very Low-Calories Ketogenic Diet, VLCKD) a …