[HTML][HTML] The laboratory rat: Age and body weight matter

A Ghasemi, S Jeddi, K Kashfi - EXCLI journal, 2021 - ncbi.nlm.nih.gov
Animal experimentation helps us to understand human biology. Rodents and, in particular,
rats are among the most common animals used in animal experiments. Reporting data on …

Nanostructured lipid carriers for improved oral delivery and prolonged antihyperlipidemic effect of simvastatin

HA Fathi, A Allam, M Elsabahy, G Fetih… - Colloids and Surfaces B …, 2018 - Elsevier
The purpose of the current study is to develop nanostructured lipid carriers (NLCs) for the
delivery of the antihyperlipidemic drug simvastatin (SIM) to increase its extremely low oral …

Reference database of hematological parameters for growing and aging rats

W Jacob Filho, CC Lima, MRR Paunksnis… - The Aging …, 2018 - Taylor & Francis
The normal hematological values in various phases of the rat life provide a valuable guide to
researchers and could be useful for experimental works. However, database information …

In Vitro Role of Pumpkin Parts as Pharma‐Foods: Antihyperglycemic and Antihyperlipidemic Activities of Pumpkin Peel, Flesh, and Seed Powders, in Alloxan …

A Hussain, T Kausar, MA Jamil… - … Journal of Food …, 2022 - Wiley Online Library
Pumpkin is a well‐known vegetable, among the members of Cucurbitaceae family, due to its
importance as pharma food. Keeping in view the antidiabetic and plasma lipids lowering …

[HTML][HTML] Retrospective analysis of the potential use of virtual control groups in preclinical toxicity assessment using the eTOX database

PSR Wright, GF Smith, KA Briggs, R Thomas… - Regulatory Toxicology …, 2023 - Elsevier
Abstract Virtual Control Groups (VCGs) based on Historical Control Data (HCD) in
preclinical toxicity testing have the potential to reduce animal usage. As a case study we …

Curcumin as a permeability enhancer enhanced the antihyperlipidemic activity of dietary green tea extract

AP Pandit, SR Joshi, PS Dalal, VC Patole - BMC complementary and …, 2019 - Springer
Background Green tea has polyphenols like flavonoids and catechins; mainly
epigallocatechin-3-gallate (EGCG), epicatechin gallate (ECG), epigallocatechin (EGC) and …

[PDF][PDF] Sex-specific reference intervals for Wistar albino rats: hematology and clinical biochemistry

R Vigneshwar, A Arivuchelvan, P Mekala… - Indian Journal of …, 2021 - researchgate.net
Wistar albino rats are the most commonly used laboratory rats for pharmacological,
toxicological and physiological experimental studies. Standardization of reference intervals …

Effect of different levels of hydrolysable tannin intake on the reproductive hormones and serum biochemical indices in healthy female rats

F Manzoor, MU Nisa, HA Hussain, N Ahmad… - Scientific Reports, 2020 - nature.com
The present work aimed to find out the effect of different levels of hydrolysable tannin (HT)
on serum hormonal profile, biochemical indices, lipid profile, apparent digestibility of …

Potential antidiabetic activity of benzimidazole derivative albendazole and lansoprazoledrugs in different doses in experimental type 2 diabetic rats

B Dik, D Coşkun, E Bahçivan… - Turkish Journal of …, 2021 - journals.tubitak.gov.tr
Aim: The aim of this study is to determine the effects of different concentrations of
albendazole and lansoprazole, which were benzimidazole derivatives, on endocrinologic …

Safety evaluation of the polyherbal formulation NawaTab: acute and subacute oral toxicity studies in rats

A Niyomchan, W Chatgat, B Chatawatee… - Evidence‐Based …, 2023 - Wiley Online Library
NawaTab is a tablet formulation developed from the Nawametho polyherbal formula used in
Surat Thani province, Southern Thailand, for the treatment of hyperlipidemia. This study …