The influence of psychosocial factors on the development and progression of cancer has
been a longstanding hypothesis since ancient times. In fact, epidemiological and clinical …

BACKGROUND: Cytokines play an important role in infection and inflammation and are
crucial mediators of the cross-talk between the brain and the immune system. Schizophrenia …

The first findings that depression is characterized by cell-mediated immune activation and
inflammation were published between 1990–1993 (Maes et al.). Recently, it was reported …

OBJECTIVE: This article reviews recent developments in cytokine biology that are relevant
to clinical psychiatry. METHOD: The authors reviewed English-language literature of the last …

Accumulating evidence supports the view that deregulation of the immune system
represents an important vulnerability factor for psychosis. In a subgroup of psychotic …

Immune parameters are elevated in psychosis, but it is unclear whether alterations are
homogenous across patients or heterogeneity exists, consistent with the hypothesis that …

Dopamine (DA) is a monoamine neurotransmitter of both central and peripheral nervous
system. Its role in the neural–immune communication has been discussed in the present …

There is an increasing body evidence pointing to a close integration between the central
nervous system (CNS) and immunological functions with lymphocytes playing therein a …

1. Parallel to the current rapid development of new immunological methods, immune
mechanisms are gaining more importance for our understanding of psychiatric disorders …

It has been hypothesized that the immune system plays a pathogenetic role in psychiatric
disorders, in particular in major depression and schizophrenia. This hypothesis is supported …