In recent years, there has been increasing interest in using biomimetic materials for bone
tissue engineering. However, the high immunogenicity and low mechanical properties of …

Flavonoids are a major group of phytoestrogens associated with physiological effects, and
ecological and social impacts. Although the estrogenic activity of flavonoids was reported by …

Abstract 3D printing enables a better control over the microstructure of bone restoring
constructs, addresses the challenges seen in the preparation of patient-specific bone …

Osteoporosis is a bone disease characterized by reduced bone mass, which leads to
increased risk of bone fractures, and poses a significant risk to public health, especially in …

Osteoporosis (OP) is one of the most common diseases in the elderly, and it is not effectively
solved by current treatments. Mesenchymal stem cells (MSCs) have multiple differentiation …

Postmenopausal osteoporosis (PMOP) is an estrogen deficiency-induced bone loss, which
has been shown an association with an altered gut microbiota (GM). Gut microbiota-bone …

Background Icariin (ICA) is a bioactive compound isolated from epimedium-derived
flavonoids that modulates bone mesenchymal stem cell osteogenesis and adipogenesis …

Over the past decades, numerous tissue-engineered constructs have been investigated for
the osteochondral repair. However, it still remains a challenge to regenerate the …

Postmenopausal osteoporosis is a systemic metabolic skeletal disease generally ascribable
to a dearth of estrogen. Whether traditional Chinese medicine is effective in management of …

Icariin has a variety of biological activities, such as lipid-lowering effects, and has attracted
widespread attention in recent years. However, it is not clear whether lipid-lowering effect is …