Fluid overload and mortality in adult critical care patients—a systematic review and meta-analysis of observational studies

AS Messmer, C Zingg, M Müller, JL Gerber… - Critical care …, 2020 - journals.lww.com
Objective: Fluid administration in combination with the increase in vasopermeability induced
by critical illness often results in significant fluid overload in critically ill patients. Recent …

[HTML][HTML] Principles of fluid management and stewardship in septic shock: it is time to consider the four D's and the four phases of fluid therapy

MLNG Malbrain, N Van Regenmortel, B Saugel… - Annals of intensive …, 2018 - Springer
In patients with septic shock, the administration of fluids during initial hemodynamic
resuscitation remains a major therapeutic challenge. We are faced with many open …

[HTML][HTML] Early restrictive or liberal fluid management for sepsis-induced hypotension

National Heart, Lung, and Blood Institute … - … England Journal of …, 2023 - Mass Medical Soc
Background Intravenous fluids and vasopressor agents are commonly used in early
resuscitation of patients with sepsis, but comparative data for prioritizing their delivery are …

Acute kidney injury in sepsis

R Bellomo, JA Kellum, C Ronco, R Wald… - Intensive care …, 2017 - Springer
Acute kidney injury (AKI) and sepsis carry consensus definitions. The simultaneous
presence of both identifies septic AKI. Septic AKI is the most common AKI syndrome in ICU …

[PDF][PDF] Fluid overload, de-resuscitation, and outcomes in critically ill or injured patients: a systematic review with suggestions for clinical practice

M Malbrain, P Marik, I Witters, C Cordemans… - Anestezjologia …, 2014 - termedia.pl
Background: Sepsis is associated with generalised endothelial injury and capillary leak and
has traditionally been treated with large volume fluid resuscitation. Some patients with …

Acute kidney injury: an increasing global concern

NH Lameire, A Bagga, D Cruz, J De Maeseneer… - The Lancet, 2013 - thelancet.com
Despite an increasing incidence of acute kidney injury in both high-income and low-income
countries and growing insight into the causes and mechanisms of disease, few preventive …

Acute kidney injury

R Bellomo, JA Kellum, C Ronco - The Lancet, 2012 - thelancet.com
Acute kidney injury (formerly known as acute renal failure) is a syndrome characterised by
the rapid loss of the kidney's excretory function and is typically diagnosed by the …

Acute kidney injury

C Ronco, R Bellomo, JA Kellum - The Lancet, 2019 - thelancet.com
Acute kidney injury (AKI) is defined by a rapid increase in serum creatinine, decrease in
urine output, or both. AKI occurs in approximately 10–15% of patients admitted to hospital …

[HTML][HTML] Fluid overload is associated with an increased risk for 90-day mortality in critically ill patients with renal replacement therapy: data from the prospective …

ST Vaara, AM Korhonen, KM Kaukonen, S Nisula… - Critical care, 2012 - Springer
Introduction Positive fluid balance has been associated with an increased risk for mortality in
critically ill patients with acute kidney injury with or without renal replacement therapy (RRT) …

Fluid management for the prevention and attenuation of acute kidney injury

JR Prowle, CJ Kirwan, R Bellomo - Nature Reviews Nephrology, 2014 - nature.com
In patients with acute kidney injury (AKI), optimization of systemic haemodynamics is central
to the clinical management. However, considerable debate exists regarding the efficacy …